Rabbit Polyclonal Antibody
Catalog No. T08-365IR
Catalog No. | Pack Size | Price (USD) | |
---|---|---|---|
T08-365IR-100 | 100 ug | $248 | |
T08-365IR-BULK | BULK | Contact Us |
References:
1. Li G, et al: Casein kinase 1 delta phosphorylates tau and disrupts its binding to microtubules. J Biol Chem. 2004 Apr 16;279(16):15938-45.
2. Noble W, et al: Cdk5 is a key factor in tau aggregation and tangle formation in vivo. Neuron. 2003 May 22;38(4):555-65.
3. Giasson BI, et al: The environmental toxin arsenite induces tau hyperphosphorylation. Biochemistry. 2002 Dec 24;41(51):15376-87.
4. Lee G, et al: The microtubule binding domain of tau protein. Neuron. 1989 Jun;2(6):1615-24.
5. Andreadis A et al: Structure and novel exons of the human tau gene. Biochemistry. 1992 Nov 3;31(43):10626-33.
Specificity:
Recognizes endogenous levels of Tau only when phosphorylated at serine 262
Cross Reactivity:
Human, Mouse and Rat
Host / Isotype / Clone#:
Rabbit, IgG
Immunogen:
The antiserum was produced against synthesized phosphopeptide derived from human Tau around the phosphorylation site of serine 262 (I-G-SP-T-E)
Purification:
Affinity chromatography
Stability:
Store at 4oC (add 0.1% NaN3) for several months, and at -20oC for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Sample Data:
Western blot analysis of extract from mouse brain tissue using a pan-Tau antibody (Lanes A and B) and Anti-phospho-Tau (Ser262) antibody (Lanes C and D)
Invasion/Metastasis, Neurobiology, p38 Pathway
STAY CONNECTED
Fax: 1-604-232-4601