Home   >    Proteins   >   Protein Kinases

PKAc beta, Active

Recombinant full-length human PKAcbeta was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag.
Catalog No. P52-10G

Shop Online

Catalog No. Pack Size Price (USD)
P52-10G-05 5 ug $226
P52-10G-10 10 ug $325
P52-10G-BULK BULK Contact Us  


The catalytic subunit C-beta of PKA (PKAcβ) is a member of the Ser/Thr protein kinase family (the PKA catalytic subunit consist of three gene products: C-alpha, C-beta, and C-gamma) and has been assigned to human chromosome region 1p36.1 (1). PKAcβ is derived from a gene distinct from C-alpha and shows tissue-specific expression. At the amino acid level C-alpha and C-beta showed 93% homology.

Gene Aliases:

PKAb; cAPKb; MGC9320; MGC41879; DKFZp781I2452; PRKACB

Genbank Number:


1. Simard, J. et al: Assignment of the gene encoding the catalytic subunit C-beta of cAMP-dependent protein kinase to the p36 band on chromosome 1. Hum. Genet. 88: 653-657, 1992.

Specific Activity:

Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


Sample Purity Data. For specific information on a given lot, see related technical data sheet.

Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Molecular Weight:

~65 kDa

 Fukuda Koichi et al., The Pseudoactive Site of ILK Is Essential for Its Binding to ?-Parvin and Localization to Focal Adhesions Molecular Cell December 2009 10.1016/j.molcel.2009.11.028

 A Thorne Curtis et al., Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α Nature Chemical Biology November 2010 10.1038/nchembio.453

 GiovannaDi Nardo,AndreaBandino,InesBarone RobertaBaravalle et al., Impact of R264C and R264H polymorphisms in human aromatase function J Steroid Biochem Mol Biol.? October 2001 10.1016/j.jsbmb.2016.09.022

 Yamaguchi Fuminori et al., S100 Proteins Modulate Protein Phosphatase 5 FunctionA LINK BETWEEN CA2+ SIGNAL TRANSDUCTION AND PROTEIN DEPHOSPHORYLATION Journal of Biological Chemistry April 2012 10.1074/jbc.M111.329771

 S Shah et al., Regulation of FcRγ function by site-specific serine phosphorylation. Journal of Leukocyte Biology September 2016 10.1189/jlb.2AB0516-228R

 Martic? Sanela et al., Electrochemical investigations into Tau protein phosphorylations Analyst March 2012 10.1039/c2an35097a

 J. Coultrap Steven et al., Improving a Natural CaMKII Inhibitor by Random and Rational Design PLoS One October 2011 10.1371/journal.pone.0025245

 SC Stolze et al., Photo-crosslinking of clinically relevant kinases using H89-derived photo-affinity probes Molecular BioSystems May 2016 10.1039/c6mb00257a

 Bhandaria Deepali et al., Cyclin-dependent kinase 5 activates guanine nucleotide exchange factor GIV/Girdin to orchestrate migration?proliferation dichotomy PNAS July 2015 10.1073/pnas.1514157112


Apoptosis/Autophagy, Cardiovascular Disease, ERK/MAPK Pathway, Neurobiology, NfkB Pathway, PKA/PKC Pathway, Ser/Thr Kinases


  PKAc gamma, Active, P53-10G

  CREB1 Protein, C49-55G

  AMPK (A2/B1/G1), Active, P48-10H

  AMPK (A1/B1/G2), Active, P55-10H



Terms of Service

Privacy Policy

Get the latest resources, updates and offers in your inbox