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IFN-gamma

Recombinant human IFN-gamma was expressed in E. coli cells and purified by proprietary chromatographic techniques.
Catalog No. I837-40N


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Catalog No. Pack Size Price (USD)
I837-40N-10 10 ug $204
I837-40N-50 50 ug $325
I837-40N-BULK BULK Contact Us  


Overview:

IFN-gamma encodes the ligand-binding chain (alpha) of the gamma interferon receptor which is a heterodimer of IFNGR1 and IFNGR2 and IFNGR1 is associated with susceptibility to Helicobacter pylori infection. IFN-gamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity (1). IFN-gamma is also a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. IFNG is a regulator of hematopoietic stem cells during homeostasis and under conditions of infectious stress (2).


Gene Aliases:

IFNG; IFG; IFI


Genbank Number:


References:


1. Shankaran, V. et.al: IFN-gamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity. Nature 410: 1107-1111, 2001.

2. Baldridge, M. T. et.al: Quiescent haematopoietic stem cells are activated by IFN-gamma in response to chronic infection. Nature 465: 793-797, 2010.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability and Shipping:

Stored at desiccated below -20oC. It is stable at 4oC between 2-7 days. For long term storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Endotoxin Level:

Less than 0.1 ng/ug (IEU/ug) of IFN-gamma.


Molecular Weight:

~17 kDa



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Apoptosis/Autophagy, Cancer, Inflammation



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