Recombinant human SCYL2 (1-520) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. S03-35G
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| S03-35G-20 | 20 ug | $215 | |
| S03-35G-50 | 50 ug | $435 | |
| S03-35G-BULK | BULK | Contact Us |
Overview:
SCYL2 or SCY1-like 2 (S. cerevisiae) is an evolutionarily conserved protein involved in SNARE sorting that is essential for normal embryonic development (1). SCYL2 serves as a regulatory factor for Vpu (viral protein U) which reducing the extent of Vpu phosphorylation and consequently enhancing BST2-mediated viral restriction (2).
Gene Aliases:
CVAK104, KIAA1360
Genbank Number:
References:
1. Borner GH. et.al: CVAK104 is a novel regulator of clathrin-mediated SNARE sorting. Traffic. 2007 Jul;8(7):893-903.
2. Miyakawa K. et.al: Interferon-induced SCYL2 limits release of HIV-1 by triggering PP2A-mediated dephosphorylation of the viral protein Vpu. Sci Signal. 2012 Oct 9;5(245):ra73. doi: 10.1126/scisignal.2003212
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
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Storage, Stability and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
~84 kDa
There are no related publications available for this product.
Inflammation, Invasion/Metastasis, Neurobiology
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