Recombinant mouse AATK (8-411) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. A02-35G
Catalog No. | Pack Size | Price (USD) | |
---|---|---|---|
A02-35G-20 | 20 ug | $215 | |
A02-35G-50 | 50 ug | $435 | |
A02-35G-BULK | BULK | Contact Us |
Overview:
AATK or apoptosis-associated tyrosine kinase contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. AATK is induced during apoptosis, and expression of this protein is a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells (1). AATK is highly detected in brain, lung, kidney, and pancreas (2). AATK is also shown to produce neuronal differentiation in a neuroblastoma cell line.
Gene Aliases:
AATYK; LMTK1; KIAA0641
Genbank Number:
References:
1. Gaozza, E. et.al: AATYK: a novel tyrosine kinase induced during growth arrest and apoptosis of myeloid cells. Oncogene 15: 3127-3135, 1997.
2. Ishikawa, K. et.al: Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. DNA Res. 5: 169-176, 1998.
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
Storage, Stability and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
~71 kDa
There are no related publications available for this product.
Apoptosis/Autophagy, Cancer, Cytoplasmic Tyrosine Kinases
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