Recombinant human SCYL1 (1-556) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. S04-35G
Catalog No. | Pack Size | Price (USD) | |
---|---|---|---|
S04-35G-20 | 20 ug | $215 | |
S04-35G-50 | 50 ug | $435 | |
S04-35G-BULK | BULK | Contact Us |
Overview:
SCYL1 is a transcriptional regulator belonging to the SCY1-like family of kinase-like proteins. SCYL1 has a divergent N-terminal kinase domain that is thought to be catalytically inactive, and can bind specific DNA sequences through its C-terminal domain. SCYL1 activates transcription of the telomerase reverse transcriptase and DNA polymerase beta genes. SCYL1 forms multimers following transfection into COS-7 cells (1). A SCYL1 binding protein has been identified that co-localized with SCYL1 in cytoplasm and shows ubiquitous expression (2).
Gene Aliases:
GKLP; HT019; NKTL; NTKL; P105; TAPK; TEIF; TRAP
Genbank Number:
References:
1. Kato, M. et.al: Identification and characterization of the human protein kinase-like gene NTKL: mitosis-specific centrosomal localization of an alternatively spliced isoform. Genomics 79: 760-767, 2002.
2. Di, Y. et.al: Cloning and characterization of a novel gene which encodes a protein interacting with the mitosis-associated kinase-like protein NTKL. J. Hum. Genet. 48: 315-321, 2003.
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
Storage, Stability and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
~85 kDa
There are no related publications available for this product.
Inflammation, Invasion/Metastasis, Neurobiology
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