Recombinant human PEAK1 (1127-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. P18-14G
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| P18-14G-20 | 20 ug | $215 | |
| P18-14G-50 | 50 ug | $435 | |
| P18-14G-BULK | BULK | Contact Us |
Overview:
PEAK1 or Pseudopodium-enriched atypical kinase 1 is a protein tyrosine kinase which belongs to NKF3 kinase family and regulates the cytoskeleton and has been shown to be involved in cancer progression (1). PEAK1 promotes anchorage-independent growth in the MDA-MB-435 human cancer cell line and promotes tumor progression of XPA-1 human pancreatic cancer cells when transplanted into the pancreas of nude mice. PEAK1 is highly expressed in spleen, followed by heart, ovary, brain, lung, kidney, and fetal brain (2).
Gene Aliases:
SGK269
Genbank Number:
References:
1. Wang, Y. et.al: Pseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progression. Proc. Nat. Acad. Sci. 107: 10920-10925, 2010.
2. Ohara, O. et.al: Characterization of size-fractionated cDNA libraries generated by the in vitro recombination-assisted method. DNA Res. 9: 47-57, 2002.
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
|
Storage, Stability and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
~100 kDa
There are no related publications available for this product.
Cancer, Cytoplasmic Tyrosine Kinases, ERK/MAPK Pathway
STAY CONNECTED
Fax: 1-604-232-4601
Toll Free: 1-866-954-6273
info@signalchem.com