mTOR activator
Catalog No. F17-901B
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| F17-901B-05 | 5 mg | $75 | |
| F17-901B-25 | 25 mg | $270 | |
| F17-901B-BULK | BULK | Contact Us |
Overview:
mTOR activator suppresses autophagy by inhibiting the fusion of autophagosomes with lysosomes leading to the accumulation of enlarged autophagosomes1. Increases ovarian follicle development2. Displays cellular protective effects from cytotoxic doses of dexamethasone3 or UV radiation4. A useful tool for probing the cellular role of mTOR5. Cell permeable.
References:
1. YJ Choy et al. PLoS One 2012 7(8):e43418
2. Y Cheng et al. PLoS One 2015 10(2):e0117769
3. S Zhao et al. Biochem. Biophys. Res. Commun. 2016 481:212
4. B Yang et al. Oncotarget 2017 481:212 Jan 4, Epub
5. C Li and HM Siragy Am. J. Physiol. Endocrinol. Metab. 2015 309:E302
CAS Registry Number:
326914-06-1
Molecular Formula:
C17H21N7O4
Appearance:
Off white powder
Molecular Weight:
387.40
Purity:
>98% (TLC); NMR (conforms)
Solubilization:
May be dissolved in DMSO (20 mg/ml); or DMF (10 mg/ml)
Aliases:
4,6-Di-4-morpholinyl-N-(4-nitrophenyl)-1,3,5-triazin-2-amine
Storage and Stability:
Store desiccated as supplied at -20oC for up to 2 years. Store solutions at -20oC for up to two months.
Molecular Structure:
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There are no related publications available for this product.
AKT/PKB Pathway, Angiogenesis, Apoptosis/Autophagy, Cancer, Cardiovascular Disease, Inflammation, Metabolic Disorder
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