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PTPRJ (CD148), Active

Recombinant full length human PTPRJ was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. P56-21G


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Catalog No. Pack Size Price (USD)
P56-21G-05 5 ug $226
P56-21G-10 10 ug $325
P56-21G-BULK BULK Contact Us  


Overview:

Receptor-type tyrosine-protein phosphatase eta or protein-tyrosine phosphatase receptor type J (R-PTP-J or CD148) are membrane protein tyrosine phosphatase initially identified on the membrane of HeLa and F-36P human leukemic cells. It contains an extracellular portion compromised of eight fibronectin III domains, a transmembrane segment and an intracytoplasmic tail which contains a single PTP domain. The presence of fibronectin III motifs in the extracellular domain suggest its possible involvement in cell adhesion processes.


Gene Aliases:

CD148; DEP1; HPTPeta; R-PTP-ETA; SCC1


Genbank Number:


References:


1. Ostman, A., et al: Expression of DEP-1, a receptor-like protein-tyrosine-phosphatase, is enhanced with increasing cell density. Proc Natl Acad Sci USA, 91. 9680-9684, 1994.

2. Honda, H., et al: Molecular cloning, characterization and chromosomal localization of a novel protein-tyrosine phosphatase, HPTPn. Blood, 84. 4186-4194, 1994.

3. Gayà A, et al: CD148, a new membrane tyrosine phosphatase involved in leukocyte


Specific Activity:

Sample Enzyme Activity Plot. For specific information on a given lot, see related technical data sheet.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability, and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

65 kDa



Product Datasheets



Safety Datasheet



There are no related publications available for this product.


RESEARCH AREAS

Cancer, Inflammation, Phosphatases


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