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PTPRS (PTP- sigma), Active

Recombinant human PTPRS (883-1210) was expressed in E.coli cells using a N-terminal GST tag.
Catalog No. P64-21G


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Catalog No. Pack Size Price (USD)
P64-21G-05 5 ug $226
P64-21G-10 10 ug $325
P64-21G-BULK BULK Contact Us  


Overview:

PTPRS is a member of a subfamily of receptor type PTPases that is characterized by the presence of an extracellular cell adhesion molecule-like motif and 2 intracellular phosphatase domains (1). The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis (2).


Gene Aliases:

PTP-sigma


Genbank Number:


References:


1. Wagner, J. et al: Olsen, A. S.: Physical mapping of receptor type protein tyrosine phosphatase sigma (PTPRS) to human chromosome 19p13.3. Genomics 38: 76-78, 1996.

2. Elchebly, M. et al: Neuroendocrine dysplasia in mice lacking protein tyrosine phosphatase sigma. Nature Genet. 21: 330-333, 1999.


Specific Activity:

Sample Enzyme Activity Plot. For specific information on a given lot, see related technical data sheet.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~63 kDa



Product Datasheets



Safety Datasheet



RESEARCH AREAS

Cancer, Cardiovascular Disease, Phosphatases


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  Phosphatase Assay Buffer I, P01-09


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