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GNAI1, Active

Recombinant human GNAI1 (2-end) was expressed in E.coli cells using an N-terminal GST tag.
Catalog No. G121-310G


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Catalog No. Pack Size Price (USD)
G121-310G-05 5 ug $160
G121-310G-10 10 ug $226
G121-310G-BULK BULK Contact Us  


Overview:

Guanine nucleotide-binding proteins (G proteins) are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits, and function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha subunit binds guanine nucleotide, can hydrolyze GTP, and can interact with other proteins. G protein subunit alpha i1(GNAI1) represents the alpha subunit of an inhibitory complex that responds to beta-adrenergic signals by inhibiting adenylate cyclase.


Gene Aliases:

Gi


Genbank Number:


References:


1. Selzer E, et al: Stimulation of human thyroid growth via the inhibitory guanine nucleotide binding (G) protein Gi: constitutive expression of the G-protein alpha subunit Gi alpha-1 in autonomous adenoma. Proc Natl Acad Sci U S A. 1993 Feb15;90(4):1609-13.

2. Bray P, et al: Human cDNA clones for an alpha subunit of Gi signal-transduction protein. Proc Natl Acad Sci U S A. 1987 Aug;84(15):5115-9.


Specific Activity:

Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability, and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

66 kDa



Product Datasheets



Safety Datasheet



There are no related publications available for this product.


RESEARCH AREAS

AKT/PKB Pathway, Cancer, Neurobiology


RELATED PRODUCTS


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  GNAI2, Active, G122-310G

  GNAI3, Active, G123-310G


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