DNA Hypomethylation Agent
Catalog No. D353-904
Catalog No. | Pack Size | Price (USD) | |
---|---|---|---|
D353-904-50 | 50 mg | $30 | |
D353-904-250 | 250 mg | $120 | |
D353-904-BULK | BULK | Contact Us |
Overview:
Specific inhibitor of DNA methyltransferase. Induces demethylation and reactivation of silenced genes. Increases stem cell reprogramming efficiency. Antitumor agent. Cell permeable.
References:
1. TS Mikkelsen et al. Nature 2008 454:49
2. AM Giraldo et al. Methods Mol. Biol. 2011 791:145
CAS Registry Number:
320-67-2
Molecular Formula:
C8H12N4O5
Appearance:
White powder
Melting Point:
226-232oC (dec.)
Molecular Weight:
244.2
Purity:
>98% (TLC)
Solubilization:
May be dissolved in DMSO (25 mg/ml); or water (12 mg/ml).
Aliases:
4-Amino-1-(beta-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one, Ladakamycin
Storage and Stability:
Store desiccated as supplied at -20oC for up to 2 years. Store solutions at -20oC for up to 1 month.
Molecular Structure:
There are no related publications available for this product.
Apoptosis/Autophagy, Cancer, Cell Cycle, Neurobiology
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