HDAC Inhibitor
Catalog No. H83-904G
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| H83-904G-5 | 5 mg | $60 | |
| H83-904G-25 | 25 mg | $240 | |
| H83-904G-BULK | BULK | Contact Us |
Overview:
A potent inhibitor of class I and II HDACs1. Cotreatment with panobinostat and an HSP90 inhibitor caused synergistic apoptosis in human CML-BC and AML cells2. A potent antimyeloma agent that overcomes drug resistance3.
References:
1. L Geng et al. Cancer Res. 2006 66:11298
2. P George et al. Blood 2005 105:1768
3. P Maiso et al. Cancer Res. 2006 66:5781
CAS Registry Number:
404950-80-7
Molecular Formula:
C21H23N3O2
Appearance:
Off-white powder
Molecular Weight:
349.43
Purity:
>98% (TLC)
Solubilization:
May be dissolved in DMSO (100 mg/ml); or ethanol (5 mg/ml, warm)
Aliases:
(E)-N-hydroxy-3-(4-((2-(2-methyl-1H-indol-3-yl)ethylamino)methyl)phenyl) crylamide; LBH-589
Storage and Stability:
Store desiccated as supplied at -20oC for up to 1 year. Store solutions at -20oC for up to one month.
Molecular Structure:
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There are no related publications available for this product.
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