Arg Methyl Transferase 1 (PRMT1) Inhibitor
Catalog No. P3695-903
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| P3695-903-50 | 50 mg | $90 | |
| P3695-903-250 | 250 mg | $360 | |
| P3695-903-BULK | BULK | Contact Us |
Overview:
Selective protein arginine methyltransferase 1 (PRMT1) inhibitor, IC50 = 1.5 uM. Displays no activity against CARM1 and Set7/9 methyltransferases. Inhibits growth of MCF7a breast cancer cells and LNCaP prostate cancer cells. Blocks androgen-induced gene expression in LNCaP cells1.
References:
1. EM Bissinger et al. Bioorg. Med. Chem. 2011 19:3717
CAS Registry Number:
17328-16-4
Molecular Formula:
C16H14Cl2N2O4S
Appearance:
Brown powder
Molecular Weight:
401.3
Purity:
>98% (TLC)
Solubilization:
May be dissolved in DMSO (50 mg/ml); or ethanol (nil)
Aliases:
N,N’-(Sulfonyldi-4,1-phenylene)bis(2-chloroacetamide)
Storage and Stability:
Store desiccated as supplied at -20oC for up to 2 years. Store solutions at -20oC for up to 1 month.
Molecular Structure:
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There are no related publications available for this product.
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