HDAC Inhibitor
Catalog No. H83-904J
Catalog No. | Pack Size | Price (USD) | |
---|---|---|---|
H83-904J-1 | 1 mg | $110 | |
H83-904J-5 | 5 mg | $330 | |
H83-904J-BULK | BULK | Contact Us |
Overview:
Potent and selective histone deacetylase (HDAC) inhibitor (Ki=3.4 nM)1. Induces reversion of ras-transformed cells to normal morphology2. Induces dedifferentiation of primordial germ cells into embryonic germ cells3. Cell permeable. Active in vivo.
References:
1. M Yoshida et al. J. Biol. Chem. 1990 265:17174
2. M Futamura et al. Oncogene 1995 10:1119
3. G Durcova-Hills et al. PLoS-One 2008 3:e3531
CAS Registry Number:
58880-19-6
Molecular Formula:
C17H22N2O3
Appearance:
Tan powder
Melting Point:
150-151oC
Molecular Weight:
302.4
Purity:
>99%
Solubilization:
May be dissolved in DMSO (15 mg/ml); or ethanol (3 mg/ml)
Aliases:
(2E,4E,6R)-7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
Storage and Stability:
Store as supplied at -20oC for up to 2 years. Store solutions at -20oC for up to 3 months.
Molecular Structure:
There are no related publications available for this product.
Cancer, Cell Cycle, Inflammation
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