Full-length recombinant human PXK was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. P99-35G
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| P99-35G-20 | 20 ug | $215 | |
| P99-35G-50 | 50 ug | $435 | |
| P99-35G-BULK | BULK | Contact Us |
Overview:
PX Domain Containing Serine/Threonine Kinase (PXK) is involved in synaptic transmission through modulating brain Na,K-ATPase subunits ATP1B1 and ATP1B3 participate in the ligand-induced internalization and degradation of epidermal growth factors. Mutation of this gene may be associated with susceptibility to systemic lupus erythematosus (SLE).
Gene Aliases:
FLJ20335; MONaKA
Genbank Number:
References:
1. Takeuchi H, et al. Characterization of PXK as a protein involved in epidermal growth factor receptor trafficking. Mol Cell Biol. 30:1689-702, 2010.
2. Zou X, et al. Expression pattern and subcellular localization of five splice isoforms of human PXK. Int J Mol Med. 16:701-7, 2005 Oct.
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
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Storage, Stability, and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
~90 kDa
There are no related publications available for this product.
Inflammation, Ser/Thr Kinases
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