Recombinant human ALK6 (BMPR1B) (149-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. B05-11G
Catalog No. | Pack Size | Price (USD) | |
---|---|---|---|
B05-11G-05 | 5 ug | $226 | |
B05-11G-10 | 10 ug | $325 | |
B05-11G-BULK | BULK | Contact Us |
Overview:
ALK6 (also known as BMPR1B) is a member of the transmembrane serine/threonine kinase that is the member of the bone morphogenetic protein (BMP) receptor, which is closely related to the activin receptors, ACVR1 and ACVR2. ALK6 is mainly involved in the endochondral bone formation and embryogenesis. ALK6 expressed in normal and cancerous prostate tissues and used in the endocrine therapy that given to the prostate cancer patients (1). ALK6 receptor trafficking also play a significant role in FOP pathogenesis and used in human T-cell differentiation (2).
Gene Aliases:
ALK-6; ALK6; CDw293
Genbank Number:
References:
1. Ide, H. et.al: Cloning of human bone morphogenetic protein type 1B receptor (BMPR-1B) and its expression in prostate cancer in comparison with other BMPRs. Oncogene 14: 1377-1382, 1997.
2. Cejalvo, T. et.al: Bone morphogenetic protein-2/4 signalling pathway components are expressed in the human thymus and inhibit early T-cell development. Immunology 121: 94-104, 2007.
Specific Activity:
Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
Storage, Stability and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
~68 kDa
There are no related publications available for this product.
AKT/PKB Pathway, Angiogenesis, Cancer, Cardiovascular Disease, JAK/STAT Pathway, Neurobiology, Ser/Thr Kinases
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