HAT Inhibitor
Catalog No. K311-903B
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| K311-903B-5 | 5 mg | $105 | |
| K311-903B-25 | 25 mg | $375 | |
| K311-903B-BULK | BULK | Contact Us |
Overview:
CPTH2 is a selective inhibitor of the histone acetyltransferase Gcn5P both in vitro and in vivo (IC50 = 0.800 uM)1. In vitro, the HAT inhibitory activity of CPTH2 was caused via bridge-interaction with histone H3. In vivo it decreased acetylation of bulk histone H3 at the H3-AcK14 site.
References:
1. F Chimenti et al. J. Med. Chem. 2009 52:530
CAS Registry Number:
357649-93-5
Molecular Formula:
C14H14ClN3S
Appearance:
white powder
Molecular Weight:
291.80
Purity:
>98% (TLC)
Solubilization:
May be dissolved in DMSO (>25 mg/ml)
Aliases:
Cyclopentylidene-[4-(4’-chlorophenyl)thiazol-2-yl]hydrazone
Storage and Stability:
Store desiccated as supplied at -20oC for up to 2 years. Store solutions at -20oC for up to one month.
Molecular Structure:
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There are no related publications available for this product.
Apoptosis/Autophagy, Cancer, Cardiovascular Disease, Cell Cycle, ERK/MAPK Pathway, Inflammation, Invasion/Metastasis, Metabolic Disorder, Neurobiology, NfkB Pathway, PKA/PKC Pathway
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