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HSP70 Protein

Recombinant full-length human HSP70 was expressed by baculovirus in Sf9 insect cells using an N-terminal His tag.
Catalog No. H34-54H


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Catalog No. Pack Size Price (USD)
H34-54H-50 50 ug $435
H34-54H-20 20 ug $215
H34-54H-BULK BULK Contact Us  


Overview:

HSP70 is a member of the heat shock protein family and is synthesized by cells of many organisms in response to stress (1). HSP70 is found mostly but not exclusively in the nucleus of unstressed cells. For several hours after a short heat shock, however, it is strongly concentrated in nucleoli (2). Nucleoli are transiently damaged by such a heat shock: their morphology changes and assembly and export of ribosomes is blocked for several hours. HSP70 helps to stabilize the morphological changes of the nucleoli.


Gene Aliases:

HSPA1A, HSP72, HSPA1, HSPA1B, HSP70-1


Genbank Number:


References:


1. Moran, L A. et al: The major heat-shock protein (hsp70) gene family: related sequences in mouse, Drosophila, and yeast. Can J Biochem Cell Biol. 1983 Jun;61(6):488-99.

2. Pelham, H R: Hsp70 accelerates the recovery of nucleolar morphology after heat shock. EMBO J. 1984 Dec 20;3(13):3095-100.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~70 kDa



RESEARCH AREAS

Cancer, Cellular Stress, p38 Pathway


RELATED PRODUCTS


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  HO1 Protein, H20-30G

  Anti-HSP27, H30-63R


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