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HUNK, Active

Recombinant full-length human HUNK was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. H08-10G


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Catalog No. Pack Size Price (USD)
H08-10G-05 5 ug $435
H08-10G-10 10 ug $655
H08-10G-BULK BULK Contact Us  


Overview:

HUNK or hormonally up-regulated Neu-associated kinase is a member of the mitogen-activated protein kinase which is essential for mammary tumor metastasis (1). Hunk deletion in mice did not alter viability, fertility, longevity, or propensity to develop tumors and it is also dispensable for murine development (2).


Gene Aliases:

MAKV, MAK-V


Genbank Number:


References:


1. Gardner, H. P.et.al: Cloning and characterization of Hunk, a novel mammalian SNF1-related protein kinase. Genomics 63: 46-59, 2000.

2. Wertheim, G. B. W. et.al: The Snf1-related kinase, Hunk, is essential for mammary tumor metastasis. Proc. Nat. Acad. Sci. 106: 15855-15860, 2009.


Specific Activity:

Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~108 kDa



There are no related publications available for this product.


RESEARCH AREAS

Cancer, Ser/Thr Kinases


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