SignalChem Enzymes and Substrates
Compatible with Promega™ Assay Systems

Quantifiable enzyme assay solutions no matter what your laboratory limitations are.
SignalChem's products are validated using various assay systems, including radiometric and Promega™ assay kits.

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VALIDATED PROMEGA™ ASSAYS

Product Name Catalog Number Substrate
ABL1, Active A03-11H Abltide
ABL1, Active A03-18H Abltide
ACK, Active A05-11G Poly (4:1 Glu, Tyr) Peptide
AKT1, Active A16-10G AKT (PKB) Substrate
AKT2, Active A17-10G Modified AKT Substrate
AKT3, Active A18-10G AKT (SGK) Substrate
ALK2, Active A06-11G Casein Protein
ALK4, Active A07-11G Casein Protein
AMPK (A1/B1/G1), Active P47-10H SAMStide
AMPK (A1/B1/G2), Active P55-10G SAMStide
AMPK (A1/B1/G2), Active P55-10H SAMStide
AMPK (A1/B1/G2), Active P55-10H SAMStide
AMPK (A2/B1/G1), Active P48-10H SAMStide
AMPK (A2/B2/G1), Active P49-10H SAMStide
ASK1, Active M13-11G MBP Protein
AURORA A, Active A28-18G MBP Protein
AURORA B, Active A31-10G MBP Protein
AXL, Active A34-11G Axltide
AXL, Active A34-11H Axltide
ALK6 (BMPR1B), Active B05-11G TGFBR1 Peptide
BMX, Active B07-10G Poly (4:1 Glu, Tyr) Peptide
BRK, Active P94-10G Poly (4:1 Glu, Tyr) Peptide
BTK, Active B10-10H Poly (4:1 Glu, Tyr) Peptide
CAMK1 gamma, Active C10-10BG Autocamtide 2
CAMK2 alpha, Active C11-10G Autocamtide 2
CAMK2 beta, Active C12-10G Autocamtide 2
CAMK2 gamma, Active C14-10G Autocamtide 2
CAMK4, Active C15-10G Autocamtide 2
CAMKK1, Active C17-10G MBP Protein
CDC7/DBF4, Active C26-10G PDKtide
CDK1/CyclinA2, Active C22-18G Histone H1 Protein
CDK2/CyclinA1, Active C29-10BG CDK2/CyclinA1, Active
CDK2/CyclinE1, Active C29-18G Histone H1 Protein
CDK2/CyclinE2, Active C29-18BG Histone H1 Protein
CDK2/CyclinA2, Active C29-10G Histone H1 Protein
CDK3/CyclinE1, Active C30-10G Histone H1 Protein
CDK4/CyclinD3, Active C31-18G Rb (C-Term) Protein
CDK5/p25, Active C33-10G Histone H1 Protein
CDK5/p35, Active C33-10BG Histone H1 Protein
CDK6/CyclinD3, Active C35-10H Histone H1 Protein
CDK9/CyclinK, Active C40-10G PDKtide
CHK1, Active C47-10G Chktide
CHK2, Active C48-10G Chktide
CK1 alpha 1L, Active C75-10G Casein Protein
CK1 alpha 1, Active C64-10G Casein, Dephosphorylated
CK1 epsilon, Active C66-10G Casein, Dephosphorylated
CK1 gamma 1, Active C68-11G Casein Protein
CK2 alpha 1, Active C70-10G Casein Protein
c-KIT, Active K06-11BG Poly (4:1 Glu, Tyr) Peptide
CLK1, Active C57-11G MBP Protein
CLK3, Active C60-10G MBP Protein
CLK4, Active C61-11G MBP Protein
c-MER, Active M51-11G Poly (4:1 Glu, Tyr) Peptide
CSK, Active C63-10G Poly (4:1 Glu, Tyr) Peptide
DAPK1, Active D01-11G MBP Protein
DCAMKL1, Active D14-10G Autocamtide 2
DCAMKL1, Active D14-11G Autocamtide 2
DDR1, Active D05-11G Modified AXLtide Substrate
DDR2, Active D06-11BG Modified AXLtide Substrate
DRAK1 (STK17A), Active S33-10G MRCL3 Peptide
DRAK2 (STK17B), Active S34-10G MRCL3 Peptide
DYRK1A, Active D09-10G DYRKtide
DYRK2, Active D10-10G DYRKtide
EGFR, Active E10-112G Poly (4:1 Glu, Tyr) Peptide
EGFR, Active E10-11G Poly (4:1 Glu, Tyr) Peptide
EIF2AK2, Active P80-11G MBP Protein
EIF2AK3, Active E11-11G SMAD3 Protein
EIF2AK4 (GCN2), Active E12-11G RS Repeat Peptide
EPHA1, Active E13-11G Poly (4:1 Glu, Tyr) Peptide
EPHA3, Active E15-11G Poly (4:1 Glu, Tyr) Peptide
EPHA6, Active E18-11G Poly (4:1 Glu, Tyr) Peptide
EPHA7, Active E19-11G Poly (4:1 Glu, Tyr) Peptide
EPHB1, Active E21-11G Poly (4:1 Glu, Tyr) Peptide
EPHB3, Active E23-11G Poly (4:1 Glu, Tyr) Peptide
ERK1, Active M29-10U MBP Protein
ERK2, Active M28-10G MBP Protein
ERK3 (MAPK6), Active M31-10G MAPKAPK5, Unactive
ERK5, Active M32-10G MBP Protein
FAK, Active P91-10G Poly (4:1 Glu, Tyr) Peptide
FAK, Active P91-11H Poly (4:1 Glu, Tyr) Peptide
FES, Active F03-10G Poly (4:1 Glu, Tyr) Peptide
FGFR1 (FLT2), Active F04-11G Poly (4:1 Glu, Tyr) Peptide
FGFR1OP-FGFR1, Active F04-19BG FGFR1OP-FGFR1, Active
FGFR2, Active F05-11G Poly (4:1 Glu, Tyr) Peptide
FGFR3, Active F06-11G Poly (4:1 Glu, Tyr) Peptide
FGFR4, Active F07-11G Poly (4:1 Glu, Tyr) Peptide
FIP1L1-PDGFR alpha, Active P12-19BG Poly (4:1 Glu, Tyr) Peptide
FLT1, Active F11-11G IGF1Rtide
FLT3, Active F12-11G MBP Protein
FMS, Active C74-11G Poly (4:1 Glu, Tyr) Peptide
FYN A, Active F15-10G Poly (4:1 Glu, Tyr) Peptide
GCK, Active M24-10G MBP Protein
GLK, Active M25-11G PKA Substrate
GRK2, Active A14-10G GRKtide
GRK5, Active G03-10G Casein Protein
GSK3 beta, Active G09-10G GSK3 Substrate
GSK3 alpha, Active G08-10G GSK3 Substrate
Haspin (GSG2), Active G10-11G Histone H3 Protein
HCK, Active H02-11G Poly (4:1 Glu, Tyr) Peptide
HER2, Active E27-11G Poly (4:1 Glu, Tyr) Peptide
HER4, Active E29-11G Poly (4:1 Glu, Tyr) Peptide
HIPK1, Active H03-11G MBP Protein
HIPK3, Active H05-13H MBP Protein
HPK1, Active M23-11G MBP Protein
IGF1R, Active I02-11H IGF1Rtide
IKK alpha, Active C51-10G IKKtide
IKK beta, Active I03-10BG IKKtide
IKK beta, Active I03-18G IKKtide
IKK epsilon, Active I04-10G IKKtide
IKK beta, Active I03-10BG IKKtide
InsR, Active I08-11G Axltide
IRAK4, Active I12-10G MBP Protein
ITK, Active I13-10G MBP Protein
ITK, Active I13-11G Poly (4:1 Glu, Tyr) Peptide
JAK3, Active J03-11G Poly (4:1 Glu, Tyr) Peptide
JNK1, Active M33-10G p38 Substrate
JNK2, Active M34-10BG ATF2 Protein
JNK3, Active M35-10BG p38 Substrate
TYK2 (JTK1), Active T21-11G Abltide
KDR, Active K01-11G Poly (4:1 Glu, Tyr) Peptide
KHS1, Active M27-10G MBP Protein
KSR2, Active K08-11G CREBtide
LCK, Active L03-10G Poly (4:1 Glu, Tyr) Peptide
LRRK2, Active L10-11G LRRKtide
LYN B, Active L13-10G SRC Substrate
MAPKAPK2, Active M40-11H HSP27tide
MAPKAPK3, Active M41-10G HSP27tide
MAPKAPK5, Active M42-10G HSP27tide
MARK1, Active M43-10G Chktide
MARK2, Active M44-10G Chktide
MASTL Protein M72-30G ARPP19 Protein
MEK1, Active M02-10G ERK1, Unactive
MEK2, Active M03-10G ERK2, Unactive
MEKK1, Active M09-11G MEK1, Unactive
MEKK2, Active M10-10G MEK1, Unactive
MELK, Active M50-11G ZIPtide
MET, Active M52-11G Poly (4:1 Glu, Tyr) Peptide
MET, Active M52-18G Poly (4:1 Glu, Tyr) Peptide
MINK1, Active M53-11G MBP Protein
MLCK, Active M62-11G MRCL3 Peptide
MLK1, Active M17-11G MBP Protein
MLK2, Active M18-11G MBP Protein
MRCK alpha, Active C27-11G S6K Substrate
MRCK beta, Active C28-11G S6K Substrate
MSK1, Active R19-10G RSK Substrate
MSK2, Active R18-10G RSK Substrate
MST1, Active S25-10G Axltide
MYLK2, Active M63-10H LC20 Protein
MYO3 beta, Active M66-11G MBP Protein
NEK1, Active N02-11G MBP Protein
NEK2, Active N03-10G MBP Protein
NEK3, Active N05-10G MBP Protein
NEK7, Active N09-10G Casein Protein
NIK, Active M22-11G MBP Protein
NUAK1, Active N19-10G Chktide
NUAK2, Active N20-10G NUAK2, Active
p38 alpha, Active M39-10BG p38 Substrate
p38 beta, Active M36-10BG p38 Substrate
p38 delta, Active M38-10BG p38 Substrate
p38 gamma, Active M37-10BG p38 Substrate
p70S6K, Active R21-10H S6K Substrate
p70S6Kb, Active R22-10G RSK Substrate
PAK1/CDC42, Active P02-10G PAKtide
PAK3, Active P04-10G MBP Protein
PAK4, Active P05-10BG Modified AKT Substrate II
PASK, Active P08-11G ZIPtide
PDGFR alpha, Active P12-18G Poly (4:1 Glu, Tyr) Peptide
PDGFR beta, Active P13-11G Poly (4:1 Glu, Tyr) Peptide
PDK1, Active P14-10H PDKtide
PIM1, Active P35-10G S6K Substrate
PIM2, Active P36-10G S6K Substrate
PKAc beta, Active P52-10G CREBtide
PKC alpha, Active P61-18G CREBtide
PKC beta I, Active P62-10G PKCtide
PKC delta, Active P64-10G CREBtide
PKC epsilon, Active P65-10G PKCtide
PKC mu, Active P72-10G CREBtide
PKC theta, Active P74-10G PKCtide
PKC gamma, Active P66-10G PKCtide
PKC beta II, Active P63-10G CREBtide
PKC zeta, Active P75-10G CREBtide
PKC iota, Active P68-10G CREBtide
PKD2 (PRKD2), Active P76-10G CREBtide
PLK1, Active P41-10H Casein, Dephosphorylated
PRKG1, Active P78-10BG RSK Substrate
PYK2, Active P92-11H Poly (4:1 Glu, Tyr) Peptide
QIK, Active S15-10G AMARA Peptide
RET, Active R02-11H IGF1Rtide
RET, Active R02-11G IGF1Rtide
RIPK1, Active R07-11G MBP Protein
RIPK2, Active R08-11G MBP Protein
RIPK3, Active R09-10G MBP Protein
ROCK1, Active R10-11G S6K Substrate
ROCK2, Active R11-11G S6K Substrate
ROCK2, Active R11-11H S6K Substrate
RON, Active M58-11G Axltide
RSK1, Active R15-10G S6K Substrate
RSK2, Active R17-10G RSK Substrate
SBK1, Active S56-10G PKA Substrate
SGK1, Active S06-10G AKT (PKB) Substrate
SGK1, Active S06-11G AKT (PKB) Substrate
SIK3, Active S12-11G AMARA Peptide
SLK, Active S11-10G Histone H3 Protein
SRC, Active S19-18G SRC Substrate
STK33, Active S46-10G MBP Protein
SYK, Active S52-10G Poly (4:1 Glu, Tyr) Peptide
TAK1-TAB1, Active M15-13G MBP Protein
TAOK1, Active T24-11G MBP Protein
TBK1, Active T02-10G MBP Protein
TGFBR1 (ALK5), Active T07-11G TGFBR1 Peptide
TGFBR2, Active T08-11G MBP Protein
TIE2, Active T04-11G Poly (4:1 Glu, Tyr) Peptide
TNIK, Active T27-11G MBP Protein
TNK1, Active T12-11G CSKtide
TOPK, Active T14-10G MBP Protein
TRKA, Active N16-11G Poly (4:1 Glu, Tyr) Peptide
TRKB, Active N17-11G Poly (4:1 Glu, Tyr) Peptide
TRKC, Active N18-11H Poly (4:1 Glu, Tyr) Peptide
TSSK1B, Active S40-10BG Chktide
TTBK1, Active T17-11G MBP Protein
TTBK2, Active T18-11G MBP Protein
TXK, Active T19-11CG MBP Protein
TYRO3, Active T22-11G Poly (4:1 Glu, Tyr) Peptide
ULK1, Active U01-11G MBP Protein
VRK2, Active V02-11G Casein Protein
WNK1, Active W02-11G MBP Protein
YES1, Active Y01-10G Poly (4:1 Glu, Tyr) Peptide
ZAK, Active Z01-10G MBP Protein
ZAP70, Active Z02-10G Poly (4:1 Glu, Tyr) Peptide
ABL1 (F317I), Active A03-12JG Abltide
ABL1 (F317L), Active A03-12IG Abltide
ABL1 (H396P), Active A03-12LG Abltide
ABL1 (Q252H), Active A03-12FG Abltide
ABL1 (V299L), Active A03-12MG Abltide
ABL1 (E255K), Active A03-12BG Abltide
ABL1 (T315I), Active A03-12DG Abltide
ABL1 (Y253F), Active A03-12EG Abltide
BRAF (G469A), Active B08-12FG MEK1, Unactive
BRAF (R506_K507insVLR), Active B08-13CG MEK1, Unactive
BRAF (T599_V600insT), Active B08-13BG MEK1, Unactive
BRAF (V600D), Active B08-12CG MEK1, Unactive
BRAF (V600K), Active B08-12DG MEK1, Unactive
BTK (C481S), Active B10-12CH Poly (4:1 Glu, Tyr) Peptide
c-KIT (D820E), Active K06-12BG Poly (4:1 Glu, Tyr) Peptide
c-KIT (N822K), Active K06-12DG Poly (4:1 Glu, Tyr) Peptide
ERN1 (IRE1), Active E31-11G Poly (4:1 Glu, Tyr) Peptide
c-KIT (V559D V654A), Active K06-12RG Poly (4:1 Glu, Tyr) Peptide
c-KIT (V559D), Active C06-12PG Poly (4:1 Glu, Tyr) Peptide
c-KIT (V560G D816V), Active C06-12TG Poly (4:1 Glu, Tyr) Peptide
c-KIT (V560G), Active C06-12SG Poly (4:1 Glu, Tyr) Peptide
c-KIT (V654A), Active K06-13G Poly (4:1 Glu, Tyr) Peptide
c-KIT (D816E), Active C06-12IG Poly (4:1 Glu, Tyr) Peptide
EGFR (A763_Y764insFHEA), Active E10-13BG Poly (4:1 Glu, Tyr) Peptide
EGFR (C775S T790M L858R), Active E10-122D2G Poly (4:1 Glu, Tyr) Peptide
EGFR (C797S L858R), Active E10-122ZG Poly (4:1 Glu, Tyr) Peptide
EGFR (C797S), Active E10-122SG Poly (4:1 Glu, Tyr) Peptide
EGFR (d746-750 C775S T790M L858R), Active E10-122E2G Poly (4:1 Glu, Tyr) Peptide
EGFR (d746-750 C797A), Active E10-122C2G Poly (4:1 Glu, Tyr) Peptide
EGFR (d746-750 C797S), Active E10-122TG Poly (4:1 Glu, Tyr) Peptide
EGFR (d746-750 T790M C797S L858R), Active E10-122YG Poly (4:1 Glu, Tyr) Peptide
EGFR (d746-750 T790M C797S), Active E10-122UG Poly (4:1 Glu, Tyr) Peptide
EGFR (d746-750 T790M L858R), Active E10-122XG Poly (4:1 Glu, Tyr) Peptide
EGFR (d746-750 T790M L798I), Active E10-122WG Poly (4:1 Glu, Tyr) Peptide
EGFR (d746-750 T790M), Active E10-122KG Poly (4:1 Glu, Tyr) Peptide
EGFR (d746-750), Active E10-122JG Poly (4:1 Glu, Tyr) Peptide
EGFR (D770_N771insNPG), Active E10-132GG Poly (4:1 Glu, Tyr) Peptide
EGFR (L858R), Active E10-122BG Poly (4:1 Glu, Tyr) Peptide
EGFR (P772_H773insNPH), Active E10-13MG Poly (4:1 Glu, Tyr) Peptide
EGFR (T790M C797S L858R), Active E10-122VG Poly (4:1 Glu, Tyr) Peptide
EGFR (T790M C797S), Active E10-122B2G Poly (4:1 Glu, Tyr) Peptide
EGFR (T790M L858R), Active E10-122DG Poly (4:1 Glu, Tyr) Peptide
EGFR (T790M), Active E10-122EG Poly (4:1 Glu, Tyr) Peptide
EGFR (C797A), Active E10-12RG Poly (4:1 Glu, Tyr) Peptide
EGFR (d746), Active E10-12IG Poly (4:1 Glu, Tyr) Peptide
EGFR (d747-749 A750P), Active E10-12MG Poly (4:1 Glu, Tyr) Peptide
EGFR (G719C), Active E10-12FG Poly (4:1 Glu, Tyr) Peptide
EGFR (G719S), Active E10-12HG Poly (4:1 Glu, Tyr) Peptide
EGFR (L858R), Active E10-12BG Poly (4:1 Glu, Tyr) Peptide
EGFR (L861Q), Active E10-12CG Poly (4:1 Glu, Tyr) Peptide
EGFR (T790M L858R), Active E10-12DG Poly (4:1 Glu, Tyr) Peptide
EGFR (T790M), Active E10-12EG Poly (4:1 Glu, Tyr) Peptide
FGFR2 (R612T), Active F05-12GG Poly (4:1 Glu, Tyr) Peptide
FGFR3 (K650Q), Active F06-12EG Poly (4:1 Glu, Tyr) Peptide
FGFR3 (K650E), Active F06-12CG Poly (6:2:5:1 Ala,Glu,Lys,Tyr) Peptide
FLT3-ITD-NPOS, Active F12-12DG MBP Protein
FLT3 (N676K), Active F12-12IG MBP Protein
FLT3 (D835Y), Active F12-12BG MBP Protein
HER2 (G776VC), Active E27-13EG Poly (4:1 Glu, Tyr) Peptide
HER2 (P780_Y781insGSP), Active E27-13DG Poly (4:1 Glu, Tyr) Peptide
JAK1 (R724H), Active J01-12BG IRS1 (Y608) Peptide
IRS1 (Y608) Peptide I40-58 CREBtide
MET (D1228H), Active M52-12HG Poly (4:1 Glu, Tyr) Peptide
MET (D1228N), Active M52-12IG Poly (4:1 Glu, Tyr) Peptide
MET (F1200I), Active M52-12GG Poly (4:1 Glu, Tyr) Peptide
MET (M1250T), Active M52-12BG Poly (4:1 Glu, Tyr) Peptide
MET (P991S), Active M52-12CG Poly (4:1 Glu, Tyr) Peptide
MET (Y1230H), Active M52-12MG Poly (4:1 Glu, Tyr) Peptide
PDGFR alpha (D842V), Active P12-12BG MBP Protein
PDGFR alpha (T674I), Active P12-12CG MBP Protein
PTC3 (NCOA4-RET), Active R02-19DG IGF1Rtide
RET (A883F), Active R02-12MG IGF1Rtide
RET (M918T), Active R02-12JH IGF1Rtide
RET (R749T), Active R02-12EG IGF1Rtide
RET (S904A), Active R02-12OG IGF1Rtide
RET (S904A), Active R02-12OH IGF1Rtide
RET (S904F), Active R02-12NG IGF1Rtide
RET (S904F), Active R02-12NH IGF1Rtide
RET (V778I), Active R02-12KG IGF1Rtide
RET (V804L), Active R02-12BG IGF1Rtide
RET (Y791F), Active R02-12CG IGF1Rtide
ROS1 (G2032R), Active R14-12BG IGF1Rtide
TIE2 (L914F), Active T04-12IG Poly (4:1 Glu, Tyr) Peptide
TIE2 (R849W), Active T04-12BG Poly (4:1 Glu, Tyr) Peptide
TIE2 (R915C), Active T04-12JG Poly (4:1 Glu, Tyr) Peptide
TIE2 (Y897H R915C), Active T04-12KG Poly (4:1 Glu, Tyr) Peptide
TIE2 (Y897S), Active T04-12EG Poly (4:1 Glu, Tyr) Peptide
TRKA (G595R), Active N16-12BG Poly (4:1 Glu, Tyr) Peptide
TRKA (G667C), Active N16-12CG Poly (4:1 Glu, Tyr) Peptide
YSK4 (MAP3K19), Active Y06-11G MBP Protein
c-KIT (d557-558), Active K06-12WG Poly (4:1 Glu, Tyr) Peptide
EGFR (D770_N771insNPG T790M), Active E10-132TG Poly (4:1 Glu, Tyr) Peptide
FGFR2 (N549H), Active F05-12G Poly (4:1 Glu, Tyr) Peptide
FGFR2 (V564F), Active F05-12FG Poly (4:1 Glu, Tyr) Peptide
FGFR3 (G697C), Active F06-12FG Poly (4:1 Glu, Tyr) Peptide
GOPC-ROS1, Active R14-19BG IGF1Rtide
TEC, Active T03-10G Poly (4:1 Glu, Tyr) Peptide
TAOK2, Active T25-11G MBP Protein
BCR-RET, Active R02-19EG IGF1Rtide
CAMK2 delta, Active C13-10G Autocamtide 2
JAK1, Active J01-11G IRS1 (Y608) Peptide
AMPK (A1/B1/G3), Active P56-10G SAMStide
AMPK (A1/B2/G1), Active P50-10H SAMStide
AMPK (A1/B2/G2), Active P45-10G SAMStide
AMPK (A2/B2/G1), Active P49-10GH SAMStide
AMPK (A2/B2/G2), Active P54-10GH SAMStide
AMPK (A2/B1/G2), Active P84-10GH
HER2 (A775_G776insYVMA), Active E27-13BG Poly (4:1 Glu, Tyr) Peptide
HER2 (V777L), Active E27-12IG Poly (4:1 Glu, Tyr) Peptide
NEK5, Active N07-11G MBP Protein
NIM1, Active N14-10G CREBtide
PLK4, Active P44-11G MBP Protein
PTC1 (CCDC6-RET), Active R02-19BG IGF1Rtide
MET (K1244R), Active M52-12QG Poly (4:1 Glu, Tyr) Peptide
RET (R813Q), Active R02-12HG IGF1Rtide
RET (R912P), Active R02-12PG IGF1Rtide
RSK2 (L608F), Active R17-12CG RSK Substrate
TPM3-ROS1, Active R14-19CG IGF1Rtide
TPR-TRKA (TRK-T1), Active N16-19BG Poly (4:1 Glu, Tyr) Peptide
TRKA (A608D), Active N16-12DG Poly (4:1 Glu, Tyr) Peptide
TRKA (F589L), Active N16-12EG Poly (4:1 Glu, Tyr) Peptide
TRKA (G595R A608D), Active N16-12FG Poly (4:1 Glu, Tyr) Peptide
YES1 (T348I), Active Y01-12BG Poly (4:1 Glu, Tyr) Peptide
DYRK1B, Active D09-10BG DYRKtide
DYRK3, Active D11-11G DYRKtide
EIF2AK1 (HRI), Active H07-10G RS Repeat Peptide
EML4-ALK (Eex13Aex20), Active A19-19G IGF1Rtide
ERN2 (IRE2), Active E32-11G MBP Protein
EPHA2, Active E14-11G Poly (4:1 Glu, Tyr) Peptide
EPHA4, Active E16-11G Poly (4:1 Glu, Tyr) Peptide
EPHB4, Active E24-11G Poly (4:1 Glu, Tyr) Peptide
ABL2, Active A04-11H Abltide
ALK (L1196M), Active A19-12GG IGF1Rtide
AURORA C, Active A33-10G MBP Protein
BLK, Active B02-10G Poly (4:1 Glu, Tyr) Peptide
BMPR2, Active B06-11H MBP Protein
BRSK1, Active B13-10G Chktide
BRSK2, Active B14-10G Chktide
CDK1/CyclinA1, Active C22-18BG Histone H1 Protein
CDK7/CyclinH1/MNAT1, Active C36-10H MBP Protein
CK1 delta, Active C65-10G Casein, Dephosphorylated
CK1 epsilon (R178C), Active C66-12BG Casein, Dephosphorylated
c-KIT (T670E), Active K06-12EG Poly (4:1 Glu, Tyr) Peptide
CLK2, Active C58-11G S6K Substrate
DAPK2, Active D02-10G LC20 Protein
DAPK3, Active D03-10G MBP Protein
FER, Active F16-11G Poly (4:1 Glu, Tyr) Peptide
FGFR1 (V561M), Active F04-13G Poly (4:1 Glu, Tyr) Peptide
FGR, Active F10-10G Poly (4:1 Glu, Tyr) Peptide
FRK, Active F14-11G Poly (4:1 Glu, Tyr) Peptide
HGK, Active M26-11G MBP Protein
IRAK1, Active I09-10G Modified AKT Substrate
LIMK1, Active L04-11G MBP Protein
LTK, Active L11-11G Abltide
LYN A, Active L13-18G Poly (4:1 Glu, Tyr) Peptide
MET (Y1230C), Active M52-12KG Poly (4:1 Glu, Tyr) Peptide
MLK4, Active M48-11G MBP Protein
MSSK1, Active S41-10G PKCtide
CK2 alpha 2, Active C71-10G CK2 Substrate
KSR1 (L639F), Active K07-122BG CREBtide
MARK3, Active M45-10G Chktide
MARK4, Active M46-10G Chktide
MEK4 (MAP2K4), Active M05-10G JNK1, Unactive
MEK5, Active M06-10G ERK5, Unactive
MEKK3, Active M11-10G MBP Protein
NEK9, Active N11-11G MBP Protein
PAK1, Active P02-10BG PAKtide
PAK6, Active P06-10G PAKtide
PAK7, Active P07-10G AKT (PKB) Substrate
PHKG1, Active P19-10G ZIPtide
PKC eta, Active P67-10G PKCtide
PKC nu, Active P73-10G CREBtide
PLK2, Active P42-10G Casein, Dephosphorylated
PLK3, Active P43-13G Casein, Dephosphorylated
PRKX, Active P81-10G PAKtide
ROS1, Active R14-11G IGF1Rtide
RSK3, Active R16-10G S6K Substrate
RSK4, Active R20-10G RSK Substrate
SGK2, Active S07-10G AKT (SGK) Substrate
SRPK1, Active S21-10G MBP Protein
SRPK2, Active S22-10G MBP Protein
STK3, Active S24-10G MBP Protein
TRKA (L657M), Active N16-12HG Poly (4:1 Glu, Tyr) Peptide
TRKC (G623R), Active N18-12CH Poly (4:1 Glu, Tyr) Peptide
TSSK2, Active S38-10G MBP Protein
ULK2, Active U02-11G MBP Protein
ULK3, Active U03-10H Casein, Dephosphorylated
c-KIT (Y823D), Active K06-12GG Poly (4:1 Glu, Tyr) Peptide
ANKK1 (SGK288), Active A20-10G Modified PKA Substrate
ASK3, Active M73-10G MEK6 (MAP2K6), Unactive
BUB1B, Active B12-11G RS Repeat Peptide
CASK, Active C19-11G PKA Substrate
CDK1/CyclinB1, Active C22-10G Histone H1 Protein
CDK6/CyclinD1, Active C35-18H Rb (C-Term) Protein
HPK1, Active M23-11BG MBP Protein
HUNK, Active H08-10G MBP Protein
IRAK2, Active I10-10BG Modified AKT Substrate
LRRK1, Active L09-11G LRRKtide
MAST3, Active M70-11G ARPP19 Protein
MATK (CTK), Active M49-10G Poly (4:1 Glu, Tyr) Peptide
NEK8, Active N10-11G MBP Protein
PDHK1, Active P57-10G PDHA1 Protein
PFTK1 (CDK14)/CyclinY, Active P15-10G Histone H1 Peptide
WNK3, Active W04-11G MBP Protein
ALK (L1196M G1202R), Active A19-12NG IGF1Rtide
ALK (R1275Q), Active A19-12LG IGF1Rtide
AMPK (A2/B1/G3), Active P85-10GH SAMStide
BRAF (V600E), Active B08-12G MEK1, Unactive
BRAF (V600A), Active B08-12EG MEK1, Unactive
c-KIT (V559D T670I), Active K06-12QG Poly (4:1 Glu, Tyr) Peptide
EGFR (D770GY), Active E10-13KG Poly (4:1 Glu, Tyr) Peptide
EGFR (K716A), Active E10-122M2G Poly (4:1 Glu, Tyr) Peptide
EGFR (K716Q L718Q), Active E10-122T2G Poly (4:1 Glu, Tyr) Peptide
EGFR (K728A T790M C797S L858R), Active E10-122Q2G Poly (4:1 Glu, Tyr) Peptide
EGFR (L792H C797S L858R), Active E10-122V2G Poly (4:1 Glu, Tyr) Peptide
EGFR (L792H), Active E10-122J2G Poly (4:1 Glu, Tyr) Peptide
EGFR (T790M C797S L858R R999A), Active E10-122R2G Poly (4:1 Glu, Tyr) Peptide
EGFR (T790M L792F C797S L858R), Active E10-122W2G Poly (4:1 Glu, Tyr) Peptide
EGFR (T790M L792H C797S L858R), Active E10-122X2G Poly (4:1 Glu, Tyr) Peptide
EGFR (L792F L858R), Active E10-122U2G Poly (4:1 Glu, Tyr) Peptide
EGFR (A763_Y764insFQEA), Active E10-132UG Poly (4:1 Glu, Tyr) Peptide
EGFR (K716A C797S L858R), Active E10-122S2G Poly (4:1 Glu, Tyr) Peptide
EGFR (L718Q), Active E10-122G2G Poly (4:1 Glu, Tyr) Peptide
EGFR (K728A), Active E10-122N2G Poly (4:1 Glu, Tyr) Peptide
EGFR (L792F), Active E10-122I2G Poly (4:1 Glu, Tyr) Peptide
EGFR (R999A), Active E10-122O2G Poly (4:1 Glu, Tyr) Peptide
EGFR (T790M L792H L858R), Active E10-122L2G Poly (4:1 Glu, Tyr) Peptide
EGFR (L718Q T790M L858R), Active E10-122H2G Poly (4:1 Glu, Tyr) Peptide
EGFR (T790M L792F L858R), Active E10-122K2G Poly (4:1 Glu, Tyr) Peptide
FGFR2 (C491S), Active F05-12JG Poly (4:1 Glu, Tyr) Peptide
FGFR2 (C491F), Active F05-12IG Poly (4:1 Glu, Tyr) Peptide
FGFR2 (C491A), Active F05-12HG Poly (4:1 Glu, Tyr) Peptide
FLT3-ITD-W51, Active F12-12CG MBP Protein
HER2 (d755-759), Active E27-12BG Poly (4:1 Glu, Tyr) Peptide
KIF5B-RET (V804L), Active R02-19HG IGF1Rtide
KIF5B-RET (V804M), Active R02-19GG IGF1Rtide
LRRK2 (G2019S), Active L10-12GG LRRKtide
MET (D1228V), Active M52-12C2G Poly (4:1 Glu, Tyr) Peptide
MET (D1228A), Active M52-12ZG Poly (4:1 Glu, Tyr) Peptide
MET (D1228G), Active M52-12B2G Poly (4:1 Glu, Tyr) Peptide
MET (D1228Y), Active M52-12D2G Poly (4:1 Glu, Tyr) Peptide
MET (G1163R), Active M52-12XG Poly (4:1 Glu, Tyr) Peptide
MET (H1094L), Active M52-12VG Poly (4:1 Glu, Tyr) Peptide
MET (H1094Y), Active M52-12WG Poly (4:1 Glu, Tyr) Peptide
MET (L1195F), Active M52-12YG Poly (4:1 Glu, Tyr) Peptide
MET (L1195V), Active M52-12TG Poly (4:1 Glu, Tyr) Peptide
MET (Y1230S), Active M52-12UG Poly (4:1 Glu, Tyr) Peptide
RET (V804M), Active R02-12GG IGF1Rtide
CDK9/CyclinK, Active C40-10G PDKtide
CDK9/CyclinK, Active C40-10G PDKtide
Anti-alpha 1-Actin A03-360M AATK Protein
Product Name Catalog Number Substrate
DNMT3A, Active D353-380G Poly (1:1 dI, dC) Acid
DNMT3B, Active D353-380BG Poly (1:1 dI, dC) Acid
EHMT1 (KMT1D), Active E317-381G Histone H3 Peptide (1-21)
EHMT2, Active E318-381G Histone H3 Peptide (1-21)
MLL1 (KMT2A), Active M341-381G Histone H3 Peptide (1-21)
MLL2 (KMT2D), Active M342-381G Histone H3 Peptide (1-21)
MLL3 (KMT2C), Active M343-381G Histone H3 Peptide (1-21)
MLL5 (KMT2E), Active M345-381G Histone H3 Peptide (1-21)
N6AMT2, Active N355-380BH Histone H3 Peptide (1-21)
PRMT1, Active P365-380G Histone H3 Peptide (1-21)
PRMT3, Active P365-380CG Histone H3 Peptide (1-21)
PRMT4, Active P365-380DG Histone H3 Peptide (1-21)
PRMT6, Active P365-380FG Histone H3 Peptide (1-21)
PRMT8, Active P365-380HG Histone H3 Peptide (1-21)
SETD1A (KMT2F), Active S342-381G Histone H3 Peptide (1-21)
SETD7, Active S344-380G Histone H1 Protein
SMYD2 (KMT3C), Active S348-380BG Histone H3 Protein
SMYD3, Active S348-380CG Histone H3 Peptide (1-21)
SUV39H1 (KMT1A), Active S350-380G Histone H3 Peptide (1-21)
SUV39H2 (KMT1B), Active S350-380BG Histone H3 Peptide (1-21)
SUV420H1 (KMT5B), Active S351-380G Histone H3 Peptide (1-21)
WHSC1 (NSD2), Active N377-381G Histone H3 Peptide (1-21)
DNMT3L, Active D353-380CG DNMT Substrate-1
COMT, Active C339-381G
DOT1L (KMT4), Active D344-381G
NNMT, Active N330-380G
PNMT, Active P331-380G
SETD2 (KMT3A), Active S343-381G
SETD6, Active S355-380G
LCMT1, Active L321-380G PP2Abeta Protein
METTL3/METTL14, Active M323-380G METTL3/METTL14 Substrate
NNMT (Dog), Active N330D-380G
Product Name Catalog Number Substrate
CDC42, Active C108-310GH GTP Solution
GNAI1, Active G121-310G GTP Solution
GNAI2, Active G122-310G GTP Solution
GNAI3, Active G123-310G GTP Solution
GNAS, Active G127-310G GTP Solution
HRAS (Mature form), Active R105-310H GTP Solution
KRAS (Mature form), Active R106-310H GTP Solution
NRAS (Mature form), Active R107-310H GTP Solution
RAC1, Active R103-310G GTP Solution
RAC2, Active R104-310H GTP Solution
RAC3, Active R102-310H GTP Solution
RhoA (Mature form), Active R144-310H GTP Solution
RhoC (Mature form), Active R144-310CH GTP Solution
RhoD (Mature form), Active R144-310DH GTP Solution
Product Name Catalog Number Substrate
UBE2A, Active U210-380H
UBE2C, Active U212-380H
UBE2D1 (UBCH5A), Active U213-380H
UBE2D2 (UBC4), Active U214-380H
UBE2D3 (UBCH5C), Active U215-380H
UBE2E3 (UBCH9), Active U219-380H
UBE2G1 (UBC7), Active U221-380H
UBE2K (UBC1), Active U227-380H
UBE2N (UBC13), Active U231-380H
UBE2O, Active U232-380G
BIRC3, Active B280-380G Ubiquitin Protein
BIRC7, Active B281-380G Ubiquitin Protein
HERC4, Active H265-381G Ubiquitin Protein
MGRN1, Active M287-380G Ubiquitin Protein
RanBP2, Active R230-381H SUMO2 Protein
RNF34 (CARP), Active R296-380G Ubiquitin Protein
RNF34L (CARP2), Active R297-380G Ubiquitin Protein
SAE1/UBA2 Complex, Active U208-380G SUMO2 Protein
TRIM37, Active T292-380G Ubiquitin Protein
UBA1 (UBE1), Active U201-380G Ubiquitin Protein
UBA6, Active U206-380G Ubiquitin Protein
UBA7(UBE1L), Active U207-380G ISG15, Protein
WWP2, Active W297-380G Ubiquitin Protein
Product Name Catalog Number Substrate
HDAC1, Active H83-30G
HDAC2, Active H84-30G
HDAC3, Active H85-30G
HDAC3/NCOR2, Active H85-38G
HDAC4, Active H86-31G
HDAC5, Active H87-31G
HDAC6, Active H88-30G
HDAC7, Active H89-31G
HDAC8, Active H90-30H
HDAC8, Active H90-30G
HDAC9, Active H91-31G
HDAC10, Active H92-31G
HDAC11, Active H93-30G
HDAC4, Active H86-31BG
Product Name Catalog Number Substrate
SIRT1, Active S35-31H
SIRT2, Active S36-30H
SIRT3, Active S37-38G
SIRT5, Active S39-30H
SIRT6, Active S40-31H
SIRT7, Active S41-30H
SIRT1, Active S35-31G
Product Name Catalog Number Substrate
PDE1A, Active P89-30H cAMP Solution
PDE1B, Active P89-30BG cAMP Solution
PDE1C, Active P89-30CG cAMP Solution
PDE2A, Active P90-30G cAMP Solution
PDE3A, Active P91-31G cAMP Solution
PDE3B, Active P91-31BG cAMP Solution
PDE4A, Active P92-31G cAMP Solution
PDE4B, Active P92-31BG cAMP Solution
PDE4C, Active P92-31CG cAMP Solution
PDE4D, Active P92-31DG cAMP Solution
PDE5A, Active P93-31G cGMP Solution
PDE6A, Active P94-31G cGMP Solution
PDE6B, Active P94-30BG cGMP Solution
PDE7A, Active P95-31G cAMP Solution
PDE7B, Active P95-30BG cAMP Solution
PDE8A, Active P96-30G cAMP Solution
PDE8B, Active P96-31BG cAMP Solution
PDE9A, Active P97-30G cGMP Solution
PDE10A, Active P98-31G cAMP Solution
Product Name Catalog Number Substrate
DGKA, Active D21-10G
PI3K (p110 alpha (E545K)/p85 alpha), Active P27-152H PI(4,5)P2:PS
PI3K (p110 alpha (N345K)/p85 alpha), Active P27-122CH PI(4,5)P2:PS
PI3K (p110 alpha (E542K)/p85 alpha), Active P27-122DH PI(4,5)P2:PS
PI3K (p110 alpha/p55 gamma), Active P27-102CH PI(4,5)P2:PS
PI3K (p110 alpha/p85 alpha), Active P27-102H PI(4,5)P2:PS
PI3K (p110 alpha/p85 alpha), Active P27-182H PI(4,5)P2:PS
PI3K (p110 beta/p85 alpha), Active P28-102H PI(4,5)P2:PS
PI3K (p110 beta/p85 beta), Active P28-102BH PI(4,5)P2:PS
PI3K (p110 delta/p85 alpha), Active P30-102H PI(4,5)P2:PS
PI3K (p120 gamma), Active P29-102H PI(4,5)P2:PS
PI4K2A, Active P21-102G PI:PS
PI4K2B, Active P22-102G PI:PS
PI4KA, Active P31-102G PI:PS
PI4KB, Active P32-102G PI:PS
PIK3C2A, Active P23-112G PI:PS
PIK3C2B, Active P24-112BG PI:PS
PIK3C2G, Active P25-112G PI:PS
PIK3C3 (Vps34), Active P26-102G PI:PS
PIP4K2A, Active P76-102AG PI(5)P:PS
PIP4K2B, Active P76-102BG PI(5)P:PS
PIP4K2C, Active P76-102CG PI(5)P:PS
PIP5K1A, Active P16-102AG PI(4)P:PS
PIP5K1B, Active P16-102BG PI(4)P:PS
PIP5K1C, Active P16-102CG PI(4)P:PS
PIP5K3 (PIKFYVE), Active P17-112BG PI(3)P:PS
SPHK1, Active S17-102G
SPHK2, Active S18-102G Kinase Dilution Buffer IX
DGKA, Active D21-10BH DLG (Dilauroyl-sn-glycerol)
SPHK2, Active S18-102G Kinase Dilution Buffer IX
DGKB, Active D22-10G DLG (Dilauroyl-sn-glycerol)
DGKE, Active D24-10G DLG (Dilauroyl-sn-glycerol)
DGKQ, Active D29-10G DLG (Dilauroyl-sn-glycerol)
DGKZ, Active D30-10G DLG (Dilauroyl-sn-glycerol)

SIGNALCHEM BIOTECH INC.


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