Enzymes, Signaling Proteins, Extracellular Ligands, Signaling Reagents, Antibodies

Catalog No.	Pack Size	Price (USD)
B279-63R-100	100 ug	$595
B279-63R-BULK	BULK	Contact Us

Catalog No.

Pack Size

Price (USD)

B279-63R-100

100 ug

$595

B279-63R-BULK

BULK

References:

1. Schimmer AD. Inhibitor of apoptosis proteins: translating basic knowledge into clinical practice. Cancer Res. 2004; 64:7183-90.

2. Rothe M et al: The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins. Cell 1995; 83:1243-52.

3. Deveraux QL et al: IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases. EMBO J. 1998; 17:2215-23.

4. Li X et al: TNF-RII and c-IAP1 mediate ubiquitinization and degradation of TRAF 2. Nature 2002; 416:345-7.

Specificity:

Recognizes the BIRC2 protein

Cross Reactivity:

Human and Mouse

Host / Isotype / Clone#:

Rabbit, IgG

Immunogen:

BIRC2 antibody was raised against a synthetic peptide corresponding to 14 amino acids at the C-terminus of human BIRC2

Purification:

Affinity chromatography

Stability:

Store at 4^oC (add 0.1% NaN₃) for several months, and at -20^oC for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Sample Data:

Western blot analysis of BIRC2 in human lung lysate with BIRC2 antibody at 1 (lane A), 2 (lane B), and 4 (lane C) ug/mL, respectively.