Rabbit Polyclonal Antibody
Catalog No. P283-63R
Catalog No. | Pack Size | Price (USD) | |
---|---|---|---|
P283-63R-100 | 100 ug | $595 | |
P283-63R-BULK | BULK | Contact Us |
References:
1. Shuai K et al: Regulation of gene-activation pathways by PIAS proteins in the immune system. Nat. Rev. Immunol.2005; 5:593-605.
2. Nelson V et al: A putative protein inhibitor of activated STAT (PIASy) interacts with p53 and inhibits p53-,ediated transactivation but not apoptosis. Apoptosis2001; 6:221-34.
3. Nishida T et al: PIASy controls ubiquitin-dependent proteasomal degradation of Ets-1. Biochem. J.2007; 405:481-8.
4. Galanty Y et al: Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks. Nature2009; 462:935-9.
Specificity:
Recognizes the PIAS4 protein
Cross Reactivity:
Human, Mouse and Rat
Host / Isotype / Clone#:
Rabbit, IgG
Immunogen:
PIAS4 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human PIAS4
Purification:
Affinity chromatography
Stability:
Store at 4oC (add 0.1% NaN3) for several months, and at -20oC for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Sample Data:
Western blot analysis of PIAS4 in rat brain tissue lysate with PIAS4 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
Sample Data:
Immunohistochemistry of PIAS4 in rat brain tissue with PIAS4 antibody at 5 ug/mL.
There are no related publications available for this product.
Apoptosis/Autophagy, Cancer, ERK/MAPK Pathway, Inflammation, JAK/STAT Pathway
STAY CONNECTED
Fax: 1-604-232-4601