Recombinant full-length human Cyclin O was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. C85-30G
Catalog No. | Pack Size | Price (USD) | |
---|---|---|---|
C85-30G-20 | 20 ug | $215 | |
C85-30G-50 | 50 ug | $435 | |
C85-30G-BULK | BULK | Contact Us |
Overview:
Cyclin O belongs to the highly conserved cyclin family. These family members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclin O plays an important role in the processes of transcription. Cyclin O also plays an important role in DNA repair and cell cycle progression. Cyclin O localizes exclusively in the nucleus (1). Cyclin O shows significant uracil-DNA glycosylase activity in which the activity of in vitro translated UDG2 was not as robust as that of the mitochondrial isoform of UNG (2).
Gene Aliases:
CCNO; CCNU; UDG2
Genbank Number:
References:
1. Caradonna, S. et.al: Affinity purification and comparative analysis of two distinct human uracil-DNA glycosylases. Exp. Cell Res. 222: 345-359, 1996.
2. Muller, S. J. et.al: Cell cycle regulation of a human cyclin-like gene encoding uracil-DNA glycosylase. J. Biol. Chem. 268: 1310-1319, 1993.
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
Storage, Stability and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
~69 kDa
There are no related publications available for this product.
Cancer, Cell Cycle
STAY CONNECTED
Fax: 1-604-232-4601