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HTRA4 Protein

Recombinant human HTRA4 (159-376) protein was expressed in E. coli cells using an N-terminal His-tag.
Catalog No. H534-31H

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Catalog No. Pack Size Price (USD)
H534-31H-20 20 ug $215
H534-31H-50 50 ug $435
H534-31H-BULK BULK Contact Us  


HTRA1 is a serine protease with a conserved trypsin domain and a PDZ domain. As other related family members, HTRA4 may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. HrtA4 may contribute to shallow trophoblast invasion in preeclampsia (1) and imply a potential application as a biomarker for this disorder (2).

Gene Aliases:


Genbank Number:


1. Wang LJ. et.al: High-temperature requirement protein A4 (HtrA4) suppresses the fusogenic activity of syncytin-1 and promotes trophoblast invasion. Mol Cell Biol. 2012 Sep;32(18):3707-17.

2. Inagaki A. et.al: Upregulation of HtrA4 in the placentas of patients with severe pre-eclampsia. Placenta. 2012 Nov;33(11):919-26


Sample Purity Data. For specific information on a given lot, see related technical data sheet.

Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Molecular Weight:

~25 kDa

Product Datasheets

There are no related publications available for this product.


Cell Cycle, Neurobiology, Ser/Thr Kinases


  HtrA (S234A) Protein, H531-36CH

  HTRA1 Protein, H531-30H

  HTRA1 (161-379) Protein, H531-32H

  HTRA4 Protein, H534-30H



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