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AMPKG1 Protein

Recombinant full-length human AMPKG1 subunit was expressed by baculovirus in Sf9 insect cells using the N-terminal GST.
Catalog No. A60-30G


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Catalog No. Pack Size Price (USD)
A60-30G-20 20 ug $314
A60-30G-50 50 ug $545
A60-30G-BULK BULK Contact Us  


Overview:

5'-AMP-activated protein kinase subunit gamma-3 (AMPKG1) is an AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. Ablation of the gamma-3 subunit is associated with impaired glycogen resynthesis in skeletal muscle In contrast, naturally occurring mutations in the gamma-3 subunit increase glycogen storage in skeletal muscle, which may enhance glycogen storage by shifting the metabolic fate of glucose from oxidation to storage.


Gene Aliases:

PRKAG1, AMPKG, MGC8666


Genbank Number:


References:


1. Barnes BR, et al. 5'-AMP-activated protein kinase regulates skeletal muscle glycogen content and ergogenics. FASEB J. 19:773-9, 2005.

2. Mu J, et al. A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle. Mol Cell. 7:1085-94, 2001.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability, and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~68 kDa



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Apoptosis/Autophagy, Cancer, Cellular Stress, Metabolic Disorder, Ser/Thr Kinases



SIGNALCHEM BIOTECH INC.


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