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Annexin 5 Protein

Recombinant full-length human Annexin 5 Protein was expressed by E. coli cells using an N-terminal His tag.
Catalog No. A61-30H


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Catalog No. Pack Size Price (USD)
A61-30H-50 50 ug $435
A61-30H-20 20 ug $215
A61-30H-BULK BULK Contact Us  


Overview:

Annexin 5 is a member of the annexin family of calcium-dependent phospholipid binding proteins. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. In vitro studies have shown that Annexin 5 is a cellular protein which plays a role in the inhibition of blood coagulation by competing for phosphatidylserine binding sites with prothrombin (1). Through affinity assays Annexin 5 has been localized on cells that expressed phosphatidylserine on the cell surface, a feature found in apoptosis as well as other forms of cell death (2).


Gene Aliases:

ANXA5, PP4, ANX5, ENX2


Genbank Number:


References:


1. Koopman, G. et al: Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis. Blood,1994; 84 (5): 1415–20.

2. Vermes, I. et al: A novel assay for apoptosis—flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. J Immunol Methods,1995; 184 (1): 39


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~37 kDa



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Apoptosis/Autophagy, Cancer, Neurobiology



SIGNALCHEM BIOTECH INC.


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