AKT Activator
Catalog No. A16-901
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| A16-901-05 | 5 mg | $75 | |
| A16-901-25 | 25 mg | $300 | |
| A16-901-BULK | BULK | Contact Us |
Overview:
Akt activator. Binds to the pleckstrin homology domain of Akt preventing membrane translocation but activating it in the cytosol. Enhances Akt phosphorylation by upstream protein kinases. Suppresses excitotoxicity-induced neuronal death in vitro and in vivo.
References:
1. H Jo et al. Proc. Natl. Acad. Sci. USA 2012 109:10581
CAS Registry Number:
305834-79-1
Molecular Formula:
C17H17ClN2O5
Appearance:
White powder
Molecular Weight:
364.80
Purity:
98% (TLC); NMR (Conforms)
Solubilization:
May be dissolved in DMSO (100 mg/ml) or ethanol (40 mg/ml, warm)
Aliases:
2-Amino-6-chloro-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic acid, ethyl ester
Storage and Stability:
Store desiccated as supplied at -20oC for up to 1 year. Store solutions at -20oC for up to 2 months.
Molecular Structure:
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There are no related publications available for this product.
AKT/PKB Pathway, Angiogenesis, Apoptosis/Autophagy, Cancer, Cardiovascular Disease, Inflammation, Invasion/Metastasis, Metabolic Disorder, Neurobiology, NfkB Pathway, WNT Signaling
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