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AURORA A, Active

Recombinant full-length mouse AURORA A was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. A28-10G

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Catalog No. Pack Size Price (USD)
A28-10G-05 5 ug $226
A28-10G-10 10 ug $325
A28-10G-BULK BULK Contact Us  


AURORA A belongs to a multigenic family of mitotic serine/threonine kinases which are involved in the control of chromosome segregation. AURORA A is involved in centrosome separation, duplication and maturation as well as in bipolar spindle assembly and stability (1). AURORA A is expressed and active at the highest level during G2-M phase of the cell cycle. Overexpression of AURORA A has been found to be correlated with the grade of various human solid tumours. Ectopic AURORA A overexpression in any culture cell line leads to polyploidy and centrosome amplification (2).

Gene Aliases:

IAK; Ark1; Ayk1; STK6; AIRK1; AU019385; AW539821; STK15; AURKA; AIK; AURA; BTAK; AURORA2

Genbank Number:


1. Dutertre, S. et al: On the role of aurora-A in centrosome function. Oncogene. 2002 Sep 9;21(40):6175-83.

2. Katayama, H. et al: The Aurora kinases: role in cell transformation and tumorigenesis. Cancer Metastasis Rev. 2003 Dec;22(4):451-64.

Specific Activity:

Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


Sample Purity Data. For specific information on a given lot, see related technical data sheet.

Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Molecular Weight:

~71 kDa

Product Datasheets


Cancer, Cell Cycle, Ser/Thr Kinases


  MBP Protein, M42-54G

  AURORA A, Active, A28-18G

  STK33, Active, S46-10G

  AURORA C, Unactive, A33-14G



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