Recombinant Human Thymosin-Beta 4 (TMSB4X) was expressed in E. coli cells.
Catalog No. T897-40N
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| T897-40N-100 | 100 ug | $193 | |
| T897-40N-1000 | 1 mg | $1172 | |
| T897-40N-BULK | BULK | Contact Us |
Overview:
The primary function of the T beta-4 member of the Thymosin-beta family is to maintain the organization of the cell’s cytoskeletal structure. Produced by myoblasts and fibroblasts, TMSB4X acts as a modulator for the production and digestion of actin and to inhibit filamentous actin polymerization. TMSB4X has also been found to induce phenotypic changes in T cell lines during early host defence mechanisms and inhibit the progression of hematopoietic pluripotent stem cells into the s-phase.
Gene Aliases:
T beta-4, Hematopoietic system regulatory peptide, Seraspenide, TMSB4X, TB4X, TMSB4
Genbank Number:
Storage, Stability and Shipping:
The lyophilized protein is stable for at least one year from date of receipt at -70oC. Upon reconstitution, this cytokine can be stored in working aliquots at 2o- 8oC for one month, or at -20oC for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Endotoxin Level:
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Molecular Weight:
5.2 kDa
Reconstitution Protocol:
Reconstitute at 100 μg/mL in sterile PBS.
Sample Cell Assay Data:
The ED (50) was determined by the dose-dependent proliferation of immortalized mouse brain endothelial cells and was found to be <0.5ng/mL.
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Purity:
Recombinant Human Thymosin-Beta 4 (TMSB4X) resolved on a 17% SDS-PAGE gel under reducing conditions and stained with Coomassie Brilliant Blue G-250.
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There are no related publications available for this product.
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