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5-Azacytidine

DNA Hypomethylation Agent
Catalog No. D353-904


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Catalog No. Pack Size Price (USD)
D353-904-50 50 mg $30
D353-904-250 250 mg $120
D353-904-BULK BULK Contact Us  


Overview:

Specific inhibitor of DNA methyltransferase. Induces demethylation and reactivation of silenced genes. Increases stem cell reprogramming efficiency. Antitumor agent. Cell permeable.

References:


1. TS Mikkelsen et al. Nature 2008 454:49

2. AM Giraldo et al. Methods Mol. Biol. 2011 791:145


CAS Registry Number:

320-67-2


Molecular Formula:

C8H12N4O5


Appearance:

White powder


Melting Point:

226-232oC (dec.)


Molecular Weight:

244.2


Purity:

>98% (TLC)


Solubilization:

May be dissolved in DMSO (25 mg/ml); or water (12 mg/ml).


Aliases:

4-Amino-1-(beta-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one, Ladakamycin


Storage and Stability:

Store desiccated as supplied at -20oC for up to 2 years. Store solutions at -20oC for up to 1 month.


Molecular Structure:



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Apoptosis/Autophagy, Cancer, Cell Cycle, Neurobiology



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