Dibutyryl cAMP
PKA Activator
Catalog No. P51-901
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| P51-901-25 | 25 mg | $60 | |
| P51-901-100 | 100 mg | $180 | |
| P51-901-BULK | BULK | Contact Us |
PKA Activator
Catalog No. P51-901
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| P51-901-25 | 25 mg | $60 | |
| P51-901-100 | 100 mg | $180 | |
| P51-901-BULK | BULK | Contact Us |
References:
1. Bartsch M et al. Biol. Chem. 2003 384:1321 2. Carranza ML et al. J. Physiol. 1998 15:511 3. Hei YJ et al. Mol. Pharmacol. 1991 39:233 4. Imamura M et al. Proc. Natl. Acad. Sci. USA 1998 95:6139 5. Xia N et al. Sci. Rep. 2016 6:20270
CAS Registry Number:
16980-89-5
Molecular Formula:
C18H23N5O8P · Na
Appearance:
White Powder
Molecular weight:
491.4
Purity:
>98% (HPLC); NMR (conforms)
solubility:
May be dissolved DMSO (50 mg/ml); water (50 mg/ml)
Aliases:
N6, O2’-Dibutyryl adenosine 3’, 5’-cyclic monophosphate sodium salt; Bucladesine Na
Storage and Stability:
Store desiccated as supplied at -20°C for up to 2 years. Store solutions at -20°C for up to 1 month.
Scientific background:
Cell-permeable cAMP analog which mimics the effect of endogenous cAMP when applied to cells (1). Activates PKA (2, 3). Induces morphological differentiation of astrocytes (4). Promotes differentiation of dopaminergic neurons from hPSCs (in cocktails with other agents) (5).
Molecular structure:
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