Kinase inhibitor (pan)
Catalog No. K10-900B
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| K10-900B-01 | 1 mg | $75 | |
| K10-900B-05 | 5 mg | $330 | |
| K10-900B-BULK | BULK | Contact Us |
Overview:
Pan-specific kinase inhibitor. Cell permeable.
CAS Registry Number:
120685-11-2
Molecular Formula:
C35H30N4O4
Appearance:
White powder
Melting Point:
N/A
Molecular Weight:
570.6
Purity:
>98% (TLC); NMR (Conforms)
Solubilization:
May be dissolved in DMSO (15 mg/ml); or ethanol (2 mg/ml)
Aliases:
1. 4'-N-Benzoyl staurosporine
2. Midostaurin
3. CGP-41251
Storage and Stability:
Store desiccated as supplied at ambient temperature for up to 2 years. Store solutions at -20oC for up to 3 months
Molecular Structure:
|
Yang Weiwei et al., EGFR-Induced and PKCε Monoubiquitylation-Dependent NF-KB Activation Upregulates PKM2 Expression and Promotes Tumorigenesis Molecular Cell November 2012 10.1016/j.molcel.2012.09.028
J. Coultrap Steven et al., Improving a Natural CaMKII Inhibitor by Random and Rational Design PLoS One October 2011 10.1371/journal.pone.0025245
Bhandaria Deepali et al., Cyclin-dependent kinase 5 activates guanine nucleotide exchange factor GIV/Girdin to orchestrate migration?proliferation dichotomy PNAS July 2015 10.1073/pnas.1514157112
AKT/PKB Pathway, Angiogenesis, Apoptosis/Autophagy, Cancer, Cardiovascular Disease, Cell Cycle, Cellular Stress, Cytoplasmic Tyrosine Kinases, ERK/MAPK Pathway, Inflammation, Invasion/Metastasis, JAK/STAT Pathway, JNK/SAPK Pathway, Metabolic Disorder, Neurobiology, NfkB Pathway, p38 Pathway, PKA/PKC Pathway, Receptor Tyrosine Kinases, Ser/Thr Kinases, WNT Signaling
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