Tyrosine kinase inhibitor (pan)
Catalog No. K11-900
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| K11-900-10 | 10 mg | $45 | |
| K11-900-50 | 50 mg | $75 | |
| K11-900-BULK | BULK | Contact Us |
Overview:
A naturally occurring flavanoid with a wide range of biological actions. Inhibits protein tyrosine kinases including epidermal growth factor receptor kinase (1,2). Phytoestrogen (3) and agonist at GPR30 (4). Displays cancer chemopreventive activity (5).
References:
1. T Akiyama et al. J. Biol. Chem. 1987 262:5592
2. C Linassier et al. Biochem. Pharmacol. 1990 39:187
3. ZC Dang et al. J. Biol. Chem. 2003 278:962
4. A Vivacqua et al. Mol. Pharmacol. 2006 70:1414
5. FH Sarker et al. Cancer Metastasis. Rev. 2002 21:265
CAS Registry Number:
446-72-0
Molecular Formula:
C15H10O5
Appearance:
Yellow solid
Melting Point:
N/A
Molecular Weight:
270.2
Purity:
98% (TLC); NMR (Conforms)
Solubilization:
May be dissolved in DMSO (25 mg/ml) or ethanol (4 mg/ml)
Aliases:
1. 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
2. 4',5,7-Trihydroxyisoflavone
Storage and Stability:
Store desiccated as supplied at -20oC for up to 1 year. Store solutions at -20oC for up to 1 week.
Molecular Structure:
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There are no related publications available for this product.
Cancer, Metabolic Disorder, Ser/Thr Kinases
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