Catalog No. P72-901
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Potent and selective ATP-competitive inhibitor of protein kinase D (PKD). IC50=3.2, 0.6 and 0.7 uM for PKD1, 2 and 3 respectively. Inhibits phorbol ester-induced PKD activation in LNCaP prostate cancer cells. Cell permeable.
1. ER Sharlow et al. PLoS One 2011 6:e25134
CAS Registry Number:
≥98% (TLC); NMR (Conforms)
Soluble in DMSO (>50mg/ml); or ethanol (8mg/ml, warm).
Storage and Stability:
Store desiccated as supplied at ambient temperature for up to 1 year. Store solutions at -20oC for up to 3 months.
There are no related publications available for this product.
Apoptosis/Autophagy, Cardiovascular Disease, ERK/MAPK Pathway, Neurobiology, NfkB Pathway, PKA/PKC Pathway, Ser/Thr Kinases