Home   >    Proteins   >   Protein Kinases

PHKG2, Active

Recombinant full-length human PHKG2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. P20-10G

Shop Online

Catalog No. Pack Size Price (USD)
P20-10G-05 5 ug $226
P20-10G-10 10 ug $325
P20-10G-BULK BULK Contact Us  


PHKG2 is the hepatic and testis isoform of the gamma subunit of phosphorylase kinase. PHKG2 gene contains 10 exons and spans 9.5 kb and maps to chromosome 16p12.1-p11.2 (1). Deficiency of PHK, a regulatory enzyme of glycogen metabolism, is responsible for 25% of all cases of glycogen storage disease and is genetically and clinically heterogeneous. Mutations in the PHKG2 gene lead to autosomal liver-specific PHK deficiency (glycogen storage disease IXc) and an increased risk of cirrhosis and at least 11 PHKG2 mutations have been identified to date (2).

Gene Aliases:


Genbank Number:


1. Burwinkel B, et al: Liver glycogenosis due to phosphorylase kinase deficiency: PHKG2 gene structure and mutations associated with cirrhosis. Hum. Molec. Genet. 7: 149-154, 1998.

2. Maichele A J, et al: Mutations in the testis/liver isoform of the phosphorylase kinase gamma subunit (PHKG2) cause autosomal liver glycogenosis in the gsd rat and in humans. Nature Genet. 14: 337-340, 1996

Specific Activity:

Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


Sample Purity Data. For specific information on a given lot, see related technical data sheet.

Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Molecular Weight:

~70 kDa

Product Datasheets

There are no related publications available for this product.


Metabolic Disorder, Ser/Thr Kinases


  MLC Peptide, M09-58

  PHKG1, Active, P19-10G



Terms of Service

Privacy Policy

Get the latest resources, updates and offers in your inbox