ERN2 or endoplasmic reticulum to nucleus signaling 2 protein, is a human homologue of the yeast Ire1 gene product which plays a role in multiple facets of the ER stress response in mammalian cells (1). This protein belongs to the protein kinase superfamily, Ser/Thr protein kinase family.
IRE1B; IRE2; IRE1-BETA; IRE2p
1. Wang, X.-Z.et.al: Cloning of mammalian Ire1 reveals diversity in the ER stress responses. EMBO J. 17: 5708-5717, 1998.
Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
Storage, Stability and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
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Angiogenesis, Cellular Stress, Neurobiology, Ser/Thr Kinases