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ERN2 (IRE2), Active

Recombinant human ERN2 (IRE2) (499-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. E32-11G


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Catalog No. Pack Size Price (USD)
E32-11G-05 5 ug $226
E32-11G-10 10 ug $325
E32-11G-BULK BULK Contact Us  


Overview:

ERN2 or endoplasmic reticulum to nucleus signaling 2 protein, is a human homologue of the yeast Ire1 gene product which plays a role in multiple facets of the ER stress response in mammalian cells (1). This protein belongs to the protein kinase superfamily, Ser/Thr protein kinase family.


Gene Aliases:

IRE1B; IRE2; IRE1-BETA; IRE2p


Genbank Number:


References:


1. Wang, X.-Z.et.al: Cloning of mammalian Ire1 reveals diversity in the ER stress responses. EMBO J. 17: 5708-5717, 1998.


Specific Activity:

Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~80 kDa



There are no related publications available for this product.


RESEARCH AREAS

Angiogenesis, Cellular Stress, Neurobiology, Ser/Thr Kinases


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