Recombinant full-length human TRIM37 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. T292-380G
Catalog No. | Pack Size | Price (USD) | |
---|---|---|---|
T292-380G-20 | 20 ug | $215 | |
T292-380G-50 | 50 ug | $435 | |
T292-380G-BULK | BULK | Contact Us |
Overview:
TRIM37 or tripartite motif containing 37 is a member of the tripartite motif (TRIM) family whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. Mutations in TRIM37 are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin.
Gene Aliases:
MUL; POB1; TEF3
Genbank Number:
References:
1. Avela, K. et al: Gene encoding a new RING-B-box-coiled-coil protein is mutated in mulibrey nanism. Nature Genet. 25: 298-301, 2000
2. Kallijarvi, J. et al: The TRIM37 gene encodes a peroxisomal RING-B-box-coiled-coil protein: classification of mulibrey nanism as a new peroxisomal disorder. Am. J. Hum. Genet. 70: 1215-1228, 2002
Specific Activity:
Sample Activity Plot. For specific information on a given lot, see related technical data sheet.
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
Storage, Stability, and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
140 kDa
There are no related publications available for this product.
Cancer, Metabolic Disorder
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