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SRMS, Active

Recombinant human SRMS (215-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. S20-11G


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Catalog No. Pack Size Price (USD)
S20-11G-05 5 ug $226
S20-11G-10 10 ug $325
S20-11G-BULK BULK Contact Us  


Overview:

SRMS is a Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites that is involved in proliferation or differentiation of keratinocytes in the skin. SRMS functions as a rapid downstream signaling intermediate following calcium-induced differentiation in keratinocytes. SRMS constitutes a new family of non-receptor tyrosine kinases that may be redundant in function (1). SRMS can act either in the membrane or at the nucleus, and may change localization patterns depending on external stimuli.


Gene Aliases:

SRM, C20orf148, dJ697K14.1


Genbank Number:


References:


1. Kohmura N. et.al: "A novel nonreceptor tyrosine kinase, Srm: cloning and targeted disruption." Mol. Cell. Biol. 14:6915-6925,1994.


Specific Activity:

Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~54 kDa



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Angiogenesis, Apoptosis/Autophagy, Cancer, Cytoplasmic Tyrosine Kinases, ERK/MAPK Pathway, Inflammation, Invasion/Metastasis, JAK/STAT Pathway



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