Full-length recombinant human GNA11 protein was expressed in E.coli cells using an N-terminal GST tag.
Catalog No. G116-30G
Catalog No. | Pack Size | Price (USD) | |
---|---|---|---|
G116-30G-20 | 20 ug | $215 | |
G116-30G-50 | 50 ug | $435 | |
G116-30G-BULK | BULK | Contact Us |
Overview:
Guanine nucleotide-binding proteins (G proteins) are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits, and function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha subunit binds guanine nucleotide, can hydrolyze GTP, and can interact with other proteins. Guanine nucleotide-binding protein subunit alpha-11 (GNA11) acts as an activator of phospholipase C. Involved in signaling of gonadotropin-releasing hormone receptor, negatively regulating cell growth. Down-regulation may be involved in human breast cancers.
Gene Aliases:
FBH; FBH2; FHH2; GNA-11; HHC2; HYPOC2
Genbank Number:
References:
1. http://www.phosphosite.org/proteinAction?id=1101&showAllSites=true
2. http://www.uniprot.org/uniprot/P29992
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
Storage, Stability, and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
66 kDa
There are no related publications available for this product.
Cancer, Cardiovascular Disease
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