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GNAI2, Active

Recombinant human GNAI2 (2-end) was expressed in E.coli cells using an N-terminal GST tag.
Catalog No. G122-310G


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Catalog No. Pack Size Price (USD)
G122-310G-05 5 ug $160
G122-310G-10 10 ug $226
G122-310G-BULK BULK Contact Us  


Overview:

Guanine nucleotide-binding proteins (G proteins) are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits, and function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha subunit binds guanine nucleotide, can hydrolyze GTP, and can interact with other proteins. G protein subunit alpha i2 (GNAI2) regulates cellular viability and migration and plays roles in a wide range of hormone signaling.


Gene Aliases:

GIP; GNAI2B; H_LUCA15.1; H_LUCA16.1


Genbank Number:


References:


1. Neves SR, et al: G protein pathways. Science. 2002 May 31; 296(5573):1636-9.

2. Raymond JR Jr, et al: Suppression of GNAI2 message in ovarian cancer. J Ovarian Res. 2014 Jan 14;7:6. doi:10.1186 /1757-2215-7-6.


Specific Activity:

Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability, and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

65 kDa



Product Datasheets



Safety Datasheet



There are no related publications available for this product.


RESEARCH AREAS

AKT/PKB Pathway, Cancer, Cardiovascular Disease, ERK/MAPK Pathway, Inflammation, Invasion/Metastasis, Metabolic Disorder, Neurobiology


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