BRSK1 is serine/threonine kinases 1 which required for presynaptic differentiation in Caenorhabditis elegans that are needed for neuronal polarization (1). BRSK1 is highly expressed in all specific adult brain regions followed by fetal brain and adult spinal cord. It is also expressed in adult heart, pancreas, testis, ovary, lung, and kidney, and in fetal liver (2).
Gm1100; MGC99905; SAD-B; SADB
1. Kishi, M. et.al: Mammalian SAD kinases are required for neuronal polarization. Science 307: 929-932, 2005.
2. Nagase, T.et.al: Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 8: 85-95, 2001.
Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
Storage, Stability and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
There are no related publications available for this product.
Apoptosis/Autophagy, Cancer, Cellular Stress, Metabolic Disorder, Ser/Thr Kinases