CAMKIβ is thought to be involved in a variety of developmental processes including development of the central nervous system (1). CAMKIβ2, an isoform of mCAMKIβ, is mainly present in the nervous system, including brain, spinal cord, trigeminal ganglion, and retina. Within the CNS, the expression of CAMKIβ2 is detected in the mantle zone suggesting its possible involvement in the differentiation of neurons (2).
Punc; Bstk3; Camk1b; CaMKlb2; caMKlb1; Pnck
1. Gardner,H.P. et al: Cloning, characterization, and chromosomal localization of Pnck, a Ca(2+)/calmodulin-dependent protein kinase. Genomics 63 (2), 279-288 (2000)
2. Ueda,T. et al: Distribution and intracellular localization of a mouse homologue of Ca2+/calmodulin-dependent protein kinase Ibeta2 in the nervous system. J. Neurochem. 73 (5), 2119-2129 (1999).
Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
Storage, Stability and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
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Cardiovascular Disease, ERK/MAPK Pathway, Neurobiology, PKA/PKC Pathway, Ser/Thr Kinases