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ERK3 (MAPK6), Active

Recombinant full-length human ERK3 (MAPK6) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. M31-10G


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Catalog No. Pack Size Price (USD)
M31-10G-05 5 ug $226
M31-10G-10 10 ug $325
M31-10G-BULK BULK Contact Us  


Overview:

ERK3 (MAPK6) or mitogen-activated protein kinase 6 is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases) which also known as extracellular signal-regulated kinases (ERKs) that are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals and tyrosine phosphorylated in response to insulin and NGF (1). ERK3 is highly expressed in various human tissues, most abundantly in skeletal muscle (2).


Gene Aliases:

ERK3; MAPK6; HsT17250; p97MAPK; PRKM6


Genbank Number:


References:


1. Boulton, T. G.et.al: ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF. Cell 65: 663-675, 1991.

2. Meloche, S. et.al: Primary structure, expression and chromosomal locus of a human homolog of rat ERK3. Oncogene 13: 1575-1579, 1996.


Specific Activity:

Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability, and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~135 kDa



Product Datasheets



RESEARCH AREAS

Angiogenesis, Apoptosis/Autophagy, Cancer, Cardiovascular Disease, ERK/MAPK Pathway, Invasion/Metastasis, Neurobiology, Ser/Thr Kinases


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