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NIM1, Active

Recombinant full-length human NIM1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. N14-10G


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Catalog No. Pack Size Price (USD)
N14-10G-05 5 ug $226
N14-10G-10 10 ug $325
N14-10G-BULK BULK Contact Us  


Overview:

NIM1 belongs to CAMK Ser/Thr protein kinase family. Unlike to other AMPK-related kinases, NIM1 cannot be phosphorylated and activated by LKB1 (1). Two somatic mutations (P333S and P411T) were found in lung neuroendocrine carcinoma and lung large cell carcinoma samples (2).


Gene Aliases:

MGC42105, NIM1K


Genbank Number:


References:


1. Jaleel M. et.al: Identification of the sucrose non-fermenting related kinase SNRK, as a novel LKB1 substrate. FEBS Lett. 579:1417-1423(2005).

2. Greenman C. et.al: Patterns of somatic mutation in human cancer genomes. Nature 446:153-158(2007).


Specific Activity:

Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~74 kDa



There are no related publications available for this product.


RESEARCH AREAS

Cancer, Cell Cycle, Ser/Thr Kinases


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