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HtrA (S234A) Protein

Recombinant streptococcus HtrA (S234A) (33-393) protein was expressed in bacterial cells using an N-terminal His-tag.
Catalog No. H531-36CH


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Catalog No. Pack Size Price (USD)
H531-36CH-20 20 ug $215
H531-36CH-50 50 ug $435
H531-36CH-BULK BULK Contact Us  


Overview:

HtrA (also designated as DegP) is a trypsin-like serine protease which contains PDZ domain and involves in heat-shock response, chaperone function, and apoptosis (1). Analysis of strains with the htrA (S234A) catalytic site mutation showed that the proteolytic activity of HtrA selectively repressed competence when translational fidelity was high but not when accuracy was low (3).


Gene Aliases:

DegP, DegP/HtrA


Genbank Number:


References:


1. Ge X. et.al: DegP primarily functions as a protease for the biogenesis of beta-barrel outer membrane proteins in the Gram-negative bacterium Escherichia coli. FEBS J. 2013 Dec 26. doi: 10.1111/febs.12701.

2. Stevens KE. et.al: Competence in Streptococcus pneumoniae is regulated by the rate of ribosomal decoding errors. MBio. 2011 Sep 20;2(5). pii: e00071-11.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~40 kDa



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Cell Cycle, Neurobiology, Ser/Thr Kinases


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