Overview:

Lambda Protein Phosphatase (lambda PP) is a Mn 2-dependent protein phosphatase composed of 221 amino acids and is encoded on ORF211 of bacteriophage lambda (1). Lambda PP has activity towards phosphorylated serine, threonine, tyrosine and histidine residues (2). It can be inhibited by vanadate ions (3).

Genbank Number:

P03772.1

References:

1. Cohen, P.T.W., and Cohen, P. 1989. Discovery of a protein phosphatase activity encoded in the genome of bacteriophage lambda. Probable identity with open reading frame 221. Biochem. J. 260, 931-934.
2. Zhuo S et al. 1993. Expression, purification, crystallization, and biochemical characterization of recombinant protein phosphatase. J. Biol. Chem. 268:17754-17761.
3. Gordon JA. 1991. Use of vanadate as protein-phosphotyrosine phosphatase inhibitor. Methods Enzymol. 201:477-82.